White-matter abnormalities in unirradiated patients cured of primary central nervous system lymphoma

被引：0

作者：

L. Kim

F. H. Hochberg

P. Shaeffer

机构：

[1] Department of Neurology,

[2] Massachusetts General Hospital,undefined

[3] Harvard Medical School,undefined

[4] Boston,undefined

[5] Massachusetts,undefined

[6] USA,undefined

[7] Brain Tumor Center,undefined

[8] Massachusetts General Hospital,undefined

[9] Cox 315,undefined

[10] 55 Fruit Street,undefined

[11] Boston,undefined

[12] MA 02114,undefined

[13] USA,undefined

[14] Department of Radiology,undefined

[15] (Neuroradiology),undefined

[16] Massachusetts General Hospital,undefined

[17] Harvard Medical School,undefined

[18] Boston,undefined

[19] Massachusetts,undefined

[20] USA,undefined

来源：

Neuroradiology | 2000年 / 42卷

关键词：

Key words Lymphoma, primary central nervous system; Chemotherapy; Magnetic resonance imaging;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

On MRI, primary brain tumors are commonly seen as contrast-enhancing masses surrounded by areas of abnormal signal on T2-weighted images. Following successful treatment tumors may no longer show contrast enhancement. The residual abnormalities are assumed to be represent “edema” and infiltrating tumor cells. We report nine patients with primary lymphoma of the central nervous system who had complete responses to intravenous methotrexate, but did not receive intrathecal chemotherapy or cranial irradiation. After complete resolution of contrast-enhancing lesions, persistent abnormalities on T2-weighted images in the region of prior tumor were initially assumed to reflect residual viable tumor. As they remained unchanged for years, however, this may not hold true in the cases in which primary central nervous system lymphoma responds to chemotherapy alone.

引用

页码：406 / 412

页数：6