Urokinase and Tissue Plasminogen Activators and Their Inhibitor PAI-1 in Human Tumors

被引:0
作者
E. S. Gershtein
N. E. Kushlinskii
机构
[1] Russian Academy of Medical Sciences,N. N. Blokhin Cancer Research Center
来源
Bulletin of Experimental Biology and Medicine | 2001年 / 131卷
关键词
urokinase plasminogen activator; tissue plasminogen activator; breast cancer; ovarian cancer; lung cancer;
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学科分类号
摘要
The content of urokinase and tissue plasminogen activators and their inhibitor PAI-1 in tumors and histologically intact tissues from patients with breast, ovarian, and non-small-cell lung cancer was measured by enzyme immunoassay. The content of urokinase plasminogen activator and PAI-1 considerably increased in all malignant tumors, however the correlation between the expression of components of the plasminogen activation system and clinical morphological feature and prognosis of the disease depends on the type of tumor.
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页码:67 / 72
页数:5
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