OSA: The new cardiovascular disease: Part II: Overview of cardiovascular diseases associated with obstructive sleep apnea

被引：0
作者：
Devulapally K. [1 ]
Pongonis Jr. R. [2 ]
Khayat R. [1 ,3 ]
机构：
[1] Division of Pulmonary, Critical Care, and Sleep Medicine, Ohio State University, Columbus, OH 43210
[2] Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL
[3] The OSU Sleep-Heart Program, Ohio State University, Columbus, OH 43210
来源：
Heart Failure Reviews | 2009年 / 14卷 / 3期
关键词：
AHI; Apnea; Apneic episodes; Arrhythmia; Blood pressure; CAD; CHF; Congestive heart failure; Coronary artery disease; HTN; Hypertension; Obstructive sleep apnea; OSA; Pulmonary hypertension; Sleep apnea; Sleep-disordered breathing; Stroke;
D O I：
10.1007/s10741-008-9101-2
中图分类号：
学科分类号：
摘要：
Obstructive sleep apnea (OSA), present in 5-15% of adults, is strongly associated with the incidence and poor outcome of hypertension, coronary artery disease, arrhythmia, heart failure, and stroke. Treatment of OSA completely reverses its cardiovascular consequences. In this review, we discuss the clinical evidence for the strong association between OSA and cardiovascular disease and present an argument for approaching OSA as a cardiovascular disease. We particularly focus on the causative relationship between OSA and hypertension, and on the increasingly recognized relationship between OSA and heart failure. © Springer Science+Business Media, LLC 2008.
引用
收藏
页码：155 / 164
页数：9
相关论文
共 140 条
  • [41] Fletcher E.C., Bao G., The rat as a model of chronic recurrent episodic hypoxia and effect upon systemic blood pressure, Sleep, 19, 10 SUPPL., (1996)
  • [42] Xie A., Et al., Neurocirculatory consequences of intermittent asphyxia in humans, J Appl Physiol, 89, 4, pp. 1333-1339, (2000)
  • [43] Khayat R.N., Et al., Cardiorespiratory effects of added dead space in patients with heart failure and central sleep apnea, Chest, 123, 5, pp. 1551-1560, (2003)
  • [44] Katragadda S., Et al., Neural mechanism of the pressor response to obstructive and nonobstructive apnea, J Appl Physiol, 83, 6, pp. 2048-2054, (1997)
  • [45] Arabi Y., Et al., Daytime blood pressure elevation after nocturnal hypoxia, J Appl Physiol, 87, 2, pp. 689-698, (1999)
  • [46] Logan A.G., Et al., High prevalence of unrecognized sleep apnoea in drug-resistant hypertension, J Hypertens, 19, 12, pp. 2271-2277, (2001)
  • [47] MacMahon S., Et al., Blood pressure, stroke, and coronary heart disease. Part 1. Prolonged differences in blood pressure: Prospective observational studies corrected for the regression dilution bias, Lancet, 335, 8692, pp. 765-774, (1990)
  • [48] Pepperell J.C., Et al., Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: A randomised parallel trial, Lancet, 359, 9302, pp. 204-210, (2002)
  • [49] Campos-Rodriguez F., Et al., Long-term effect of continuous positive airway pressure on BP in patients with hypertension and sleep apnea, Chest, 132, 6, pp. 1847-1852, (2007)
  • [50] Robinson G.V., Et al., Continuous positive airway pressure does not reduce blood pressure in nonsleepy hypertensive OSA patients, Eur Respir J, 27, 6, pp. 1229-1235, (2006)
12345678910