BODIPY-based Fluorescent Probe for the Detection of Cysteine in Living Cells

被引:0
作者
Nannan Wang
Xin Ji
Han Wang
Xianhui Wang
Yanfang Tao
Weili Zhao
Jian Zhang
机构
[1] Henan University,Key Laboratory for Special Functional Materials of Ministry of Education, School of Materials Science and Engineering
来源
Analytical Sciences | 2020年 / 36卷
关键词
BODIPY; cysteine; fluorescent probe; bioimaging;
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学科分类号
摘要
Cysteine (Cys), as one of the important amino acids, plays a vital role in various physiological and pathological processes. Hence, it is meaningful to develop a convenient and sensitive detection method. Herein, a novel BODIPY-based fluorescent probe (BDP-DM) was developed, which had a higher selectivity for Cys than other amino acids, including homocysteine (Hcy) and glutathione (GSH). Ultimately, we concluded that the BDP-DM probe could be used to successfully detected intracellular Cys in living HeLa cells.
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页码:1317 / 1321
页数:4
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