Detrimental alteration of mesenchymal stem cells by an articular inflammatory microenvironment results in deterioration of osteoarthritis

被引:0
|
作者
Mengqiang Fan
Peijian Tong
Li Yan
Ting Li
Jiadan Ren
Jiefeng Huang
Wenxi Du
Li Zhou
Letian Shan
机构
[1] The First Affiliated Hospital,Cell Resource Bank and Integrated Cell Preparation Center of Xiaoshan District
[2] Zhejiang Chinese Medical University,Department of Plastic & Reconstructive Surgery
[3] Hangzhou Regional Cell Preparation Center (Shangyu Biotechnology Co.,College of Pharmaceutical Sciences
[4] Ltd),undefined
[5] Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital,undefined
[6] Hangzhou Medical College),undefined
[7] Zhejiang Chinese Medical University,undefined
来源
BMC Medicine | / 21卷
关键词
Knee osteoarthritis; Synovial fluid; Human umbilical cord mesenchymal stem cells; Articular inflammatory microenvironment; MMP13; c-Jun; MAPKs;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [1] Detrimental alteration of mesenchymal stem cells by an articular inflammatory microenvironment results in deterioration of osteoarthritis
    Fan, Mengqiang
    Tong, Peijian
    Yan, Li
    Li, Ting
    Ren, Jiadan
    Huang, Jiefeng
    Du, Wenxi
    Zhou, Li
    Shan, Letian
    BMC MEDICINE, 2023, 21 (01)
  • [2] Roles of Microenvironment on Mesenchymal Stem Cells Therapy for Osteoarthritis
    Zhang, Haiyan
    Jin, Chaoying
    Hua, Jiaqing
    Chen, Zuxiang
    Gao, Wenxin
    Xu, Wenting
    Zhou, Li
    Shan, Letian
    JOURNAL OF INFLAMMATION RESEARCH, 2024, 17 : 7069 - 7079
  • [3] Mesenchymal Stem Cells for Treating Articular Cartilage Defects and Osteoarthritis
    Wang, Yu
    Yuan, Mei
    Guo, Quan-yi
    Lu, Shi-bi
    Peng, Jiang
    CELL TRANSPLANTATION, 2015, 24 (09) : 1661 - 1678
  • [4] The roles of mesenchymal stem cells in tumor inflammatory microenvironment
    Sun, Zhao
    Wang, Shihua
    Zhao, Robert Chunhua
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2014, 7
  • [5] The roles of mesenchymal stem cells in tumor inflammatory microenvironment
    Zhao Sun
    Shihua Wang
    Robert Chunhua Zhao
    Journal of Hematology & Oncology, 7
  • [6] Mesenchymal stem cells as a vector for the inflammatory prostate microenvironment
    Brennen, W. Nathaniel
    Denmeade, Samuel R.
    Isaacs, John T.
    ENDOCRINE-RELATED CANCER, 2013, 20 (05) : R269 - R290
  • [7] Inflammatory Microenvironment Changes the Secretory Profile of Mesenchymal Stem Cells to Recruit Mesenchymal Stem Cells
    Xing, Junchao
    Hou, Tianyong
    Jin, Huiyong
    Luo, Fei
    Chang, Zhengqi
    Li, Zhiqiang
    Xie, Zhao
    Xu, Jianzhong
    CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2014, 33 (04) : 905 - 919
  • [8] Alleviation of osteoarthritis by intra-articular transplantation of circulating mesenchymal stem cells
    Lin, Weiping
    Yang, Zhengmeng
    Shi, Liu
    Wang, Haixing
    Pan, Qi
    Zhang, Xiaoting
    Zhang, Peng
    Lin, Sien
    Li, Gang
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, 636 : 25 - 32
  • [9] Intra-articular mesenchymal stem cells for cartilage repair in osteoarthritis of the knee
    Park, Y.
    Ha, C.
    Kim, M.
    CYTOTHERAPY, 2020, 22 (05) : S30 - S31
  • [10] Mesenchymal stem cells and their microenvironment
    Liu, Jiaxi
    Gao, Jinfang
    Liang, Zixie
    Gao, Chong
    Niu, Qing
    Wu, Fengping
    Zhang, Liyun
    STEM CELL RESEARCH & THERAPY, 2022, 13 (01)