An approach to the influenza chimeric subunit vaccine (3M2e-HA2-NP) provides efficient protection against lethal virus challenge

被引:0
作者
Maryam Saleh
Jamileh Nowroozi
Behrokh Farahmand
Fatemeh Fotouhi
机构
[1] Islamic Azad University,Department of Microbiology, Faculty of Biological Science
[2] Pasteur Institute of Iran,Department of Influenza and Other Respiratory Viruses
来源
Biotechnology Letters | 2020年 / 42卷
关键词
3M2e-HA2-NP; Chimeric protein; Influenza; Protective capability; Vaccination;
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页码:1147 / 1159
页数:12
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  • [1] Aguilar JC(2007)Vaccine adjuvants revisited Vaccine 25 3752-3762
  • [2] Rodríguez EG(2012)Increased immunogenicity and protective efficacy of influenza M2e fused to a tetramerizing protein PLoS ONE 7 e46395-e2836
  • [3] Andersson A-MC(2017)Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity Cell Death Dis 8 e2836-3369
  • [4] Håkansson KO(2013)The adjuvant effect of MF59 is due to the oil-in-water emulsion formulation, none of the individual components induce a comparable adjuvant effect Vaccine 31 3363-148
  • [5] Jensen BAH(2019)Chimeric hemagglutinin-based influenza virus vaccines induce protective stalk-specific humoral immunity and cellular responses in mice ImmunoHorizons 3 133-551
  • [6] Christensen D(2006)The universal influenza vaccine M2e-HBc administered intranasally in combination with the adjuvant CTA1-DD provides complete protection Vaccine 24 544-136
  • [7] Andersen P(2015)M2e-based universal influenza A vaccines Vaccines 3 105-89
  • [8] Thomsen AR(2017)Protein nanoparticle vaccine based on flagellin carrier fused to influenza conserved epitopes confers full protection against influenza A virus challenge Virology 509 82-151
  • [9] Christensen JP(2014)Broadly neutralizing hemagglutinin stalk-specific antibodies require FcγR interactions for protection against influenza virus in vivo Nat Med 20 143-12
  • [10] Bhat P(2010)Cloning, expression and purification of the influenza A (H9N2) virus M2e antigen and truncated Protein Express Purif 70 7-40