Assessment of biosafety and toxicity of hydrophilic gel for implantation in experimental in vitro and in vivo models

[1] Krewski D(2010)Toxicity testing in the 21st century: a vision and a strategy J Toxicol Environ Health B Crit Rev 13 51-138

[2] Acosta D(2011)Toxicological screening J Pharmacol Pharmacother 2 74-79

[3] Andersen M(2018)In vivo safety and efficacy testing of a thermally triggered injectable hydrogel scaffold for bone regeneration and augmentation in a rat model Oncotarget. 9 18277-18295

[4] Parasuraman S(2019)Effectiveness and Safety of Implant-Based Breast Reconstruction in Locally Advanced Breast Carcinoma: A Matched Case-Control Study Breast Care 14 200-210

[5] Thorpe AA(2015)The prognosis of breast cancer patients after mastectomy and immediate breast reconstruction: a meta-analysis PLoS One 10 e0125655-685

[6] Freeman C(2019)Injectable hydrogels for localized cancer therapy Front Chem 7 675-97

[7] Farthing P(2019)In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment Nat Nanotechnol 14 89-879

[8] Vieira RAC(2018)Peri-tumor administration of 5-fluorouracil sol-gel using a hollow microneedle for treatment of gastric cancer Drug Deliv 25 872-345

[9] Ribeiro LM(2018)Nepafenac loaded silica nanoparticles dispersed in-situ gel systems: development and characterization Int J Biol Macromol 110 336-14

[10] GFA C(2020)Hydrogels in the clinic Bioeng Transl Med 5 e10158-80

[1] Krewski D(2010)Toxicity testing in the 21st century: a vision and a strategy J Toxicol Environ Health B Crit Rev 13 51-138

[2] Acosta D(2011)Toxicological screening J Pharmacol Pharmacother 2 74-79

[3] Andersen M(2018)In vivo safety and efficacy testing of a thermally triggered injectable hydrogel scaffold for bone regeneration and augmentation in a rat model Oncotarget. 9 18277-18295

[4] Parasuraman S(2019)Effectiveness and Safety of Implant-Based Breast Reconstruction in Locally Advanced Breast Carcinoma: A Matched Case-Control Study Breast Care 14 200-210

[5] Thorpe AA(2015)The prognosis of breast cancer patients after mastectomy and immediate breast reconstruction: a meta-analysis PLoS One 10 e0125655-685

[6] Freeman C(2019)Injectable hydrogels for localized cancer therapy Front Chem 7 675-97

[7] Farthing P(2019)In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment Nat Nanotechnol 14 89-879

[8] Vieira RAC(2018)Peri-tumor administration of 5-fluorouracil sol-gel using a hollow microneedle for treatment of gastric cancer Drug Deliv 25 872-345

[9] Ribeiro LM(2018)Nepafenac loaded silica nanoparticles dispersed in-situ gel systems: development and characterization Int J Biol Macromol 110 336-14

[10] GFA C(2020)Hydrogels in the clinic Bioeng Transl Med 5 e10158-80