Celiac disease: a clinical review

被引:0
作者
Badr Al-Bawardy
D. Chamil Codipilly
Alberto Rubio-Tapia
David H. Bruining
Stephanie L. Hansel
Joseph A. Murray
机构
[1] Mayo Clinic,Division of Gastroenterology & Hepatology
[2] Mayo Clinic,Department of Internal Medicine
来源
Abdominal Radiology | 2017年 / 42卷
关键词
Celiac disease; Enteropathy; Sprue; Gluten free; Refractory; imaging;
D O I
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学科分类号
摘要
Celiac disease (CD) is an immune-mediated inflammatory enteropathy triggered by gluten exposure in genetically susceptible individuals. It has a high prevalence approaching 1% of the US population. A high index of suspicion is warranted to diagnose CD as frequently patients present with extraintestinal or atypical manifestations. CD is diagnosed by a combination of serum serologies and duodenal biopsies. The majority of patients will respond to a lifelong gluten-free diet which is the cornerstone of therapy. Complications such as refractory CD, ulcerative jejunoileitis, enteropathy associated T-cell lymphoma and small bowel adenocarcinoma occur in a minority of patients.
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页码:351 / 360
页数:9
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