Effect of Mobile Phase pH* on Chromatographic Behaviour in Chiral Ligand-Exchange Thin-Layer Chromatography (CLETLC) of Amino Acid Enantiomers

被引：0
作者：
B. Polak
W. Gołkiewicz
T. Tuzimski
机构：
[1] Medical University of Lublin,Department of Physical Chemistry
来源：
Chromatographia | 2006年 / 63卷
关键词：
Thin-layer-chromatography; Chiral ligand-exchange; Mobile-phase pH; Amino acids;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The enantiomers of some amino acids have been separated on commercial chiral TLC plates in reversed-phase mode. The effect of the pH* of the aqueous-organic mobile phase on the retention and mobility of the enantiomers and on selectivity was investigated. It was shown that for most of the amino acids investigated the highest enantioselectivity was obtained at pH* 3–4 or 6–7. The drift and disturbance of the baseline on the chromatograms were also much smaller at pH* 3–4 and 6–7.
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页码：197 / 201
页数：4
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