Hyponatremia in heart failure

被引:0
作者
Dimitrios Farmakis
Gerasimos Filippatos
John Parissis
Dimitrios Th. Kremastinos
Mihai Gheorghiade
机构
[1] Attikon University Hospital,Second Department of Cardiology, Heart Failure Unit
[2] Northwestern University,Feinberg School of Medicine
来源
Heart Failure Reviews | 2009年 / 14卷
关键词
Hyponatremia; Heart failure; Vasopressin; Tolvaptan; Conivaptan; Lixivaptan;
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摘要
Hyponatremia is the most common electrolyte abnormality found in hospitalized patients with heart failure. It may occur in patients who have hypovolemic, hypervolemic, or euvolemic state. It is usually not corrected by available therapies. It is a major predictor of prognosis, and correction of hyponatremia can be effectively accomplished by vasopressin antagonists. However, it still remains to be seen whether the normalization of serum sodium with vasopressin antagonists will also lead to an improved long-term prognosis.
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