An approach to the estimation of the lateral phenotype in children has been developed. During the study, more than 20 lateral phenotypes were identified in six-to seven-year-old children. The most frequent are the following lateral phenotypes: dextrality (motor and sensory), motor dextrality and sensory sinistrality, and motor dextrality and sensory ambidexterity (with a dominant left ear and right eye and with a dominant right ear and left eye). Unilateral left-handers accounted for 0.1% of all children studied; thus, the use of the laterality profile of motor functions as a "marker" of the brain functional asymmetry is rather questionable. © Pleiades Publishing, Inc. 2007.