Synthesis, conformational and pharmacological studies on dermorphin N-terminal tetrapeptide analogues

被引：0

作者：

Andrea Calderan

Paolo Ruzza

Biancamaria Ancona

Lorenzo Cima

Pietro Giusti

Gianfranco Borin

机构：

[1] University of Padova,Biopolymer Research Centre, CNR, c/o Department of Organic Chemistry

[2] University of Padova,Department of Pharmacology

来源：

Letters in Peptide Science | 1998年 / 5卷

关键词：

dermorphin analogues; opioid peptides; receptor selectivity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Dermorphin structure-activity relationships toward μ and δ opioid receptors were investigated using a series of synthetic peptides, in which the aromatic residues at positions 1 or/and 3 of the N-terminal tetrapeptide analogue H-Tyr-d-Arg-Phe-β-Ala-NH2 were replaced by unnatural or constrained amino acids.

引用

页码：71 / 73

页数：2