Glypican-1 Promotes Tumorigenesis by Regulating the PTEN/Akt/β-Catenin Signaling Pathway in Esophageal Squamous Cell Carcinoma

被引:0
作者
Jing Li
Yanjie Chen
Cheng Zhan
Jimin Zhu
Shuqiang Weng
Ling Dong
Taotao Liu
Xizhong Shen
机构
[1] Fudan University,Department of Gastroenterology, Zhongshan Hospital, Key Laboratory of Medical Molecule Virology, Ministry of Education and Health, Shanghai Institute of Liver Diseases
[2] Zhongshan Hospital,Department of Thoracic Surgery
[3] Fudan University,undefined
来源
Digestive Diseases and Sciences | 2019年 / 64卷
关键词
Glypican-1; Esophageal squamous cell carcinoma; Cell proliferation; Epithelial–mesenchymal transition; PTEN/Akt/β-Catenin signaling pathway;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1493 / 1502
页数:9
相关论文
共 91 条
  • [1] Rustgi AK(2014)Esophageal carcinoma N Engl J Med 371 2499-2509
  • [2] El-Serag HB(2017)International cancer seminars: a focus on esophageal squamous cell carcinoma Ann Oncol 28 2086-2093
  • [3] Murphy G(2002)The role of glypicans in mammalian development Biochim Biophys Acta 1573 241-246
  • [4] McCormack V(2009)Glypican-1 controls brain size through regulation of fibroblast growth factor signaling in early neurogenesis Neural Dev 4 33-1178
  • [5] Abedi-Ardekani B(2014)Autoregulation of glypican-1 by intronic microRNA-149 fine tunes the angiogenic response to FGF2 in human endothelial cells J Cell Sci 127 1169-16053
  • [6] Song HH(2003)Heparan sulfate proteoglycans as regulators of fibroblast growth factor-2 signaling in brain endothelial cells. Specific role for glypican-1 in glioma angiogenesis J Biol Chem 278 16045-2026
  • [7] Filmus J(2006)Glypican-1 is frequently overexpressed in human gliomas and enhances FGF-2 signaling in glioma cells Am J Pathol 168 2014-1253
  • [8] Jen YH(2008)Discovery of a novel molecule that regulates tumor growth and metastasis Sci World J 8 1250-1191
  • [9] Musacchio M(2017)Elevated glypican-1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma Cancer Med 6 1181-75
  • [10] Lander AD(2016)Overexpression of glypican-1 implicates poor prognosis and their chemoresistance in oesophageal squamous cell carcinoma Br J Cancer 115 66-674