Comparative studies of four Drosophila P-insertion mutants with memory defects

被引：4
作者：
Yu. V. Bragina
N. G. Kamyshev
机构：
[1] Lab. for Comparative Behav. Genet., I. P. Pavlov Institute of Physiology, Russian Academy of Sciences, 199034 St. Petersburg
来源：
Neuroscience and Behavioral Physiology | 2003年 / 33卷 / 1期
基金：
俄罗斯基础研究基金会;
关键词：
Conditioned reflex courtship suppression; Counterconditioning; Drosophila melanogaster; Learning; Memory; P-insertion mutants;
D O I：
10.1023/A:1021183432491
中图分类号：
学科分类号：
摘要：
Studies of conditioned reflex courtship suppression in mutant Drosophila males in two tests - a memory retention test (with a virgin female) and a repeat training test (with a fertilized female) - yielded experimental support for a previously suggested physiological model of the acquisition of this reflex. Mutations altered both types of conditioned association suggested in the model, i.e., the association between the conditioned and unconditioned stimuli (lat, rut, dnc, amn, and P153) and the association between the conditioned stimulus and the aversive motivational system mediating the action of the unconditioned stimulus (P171). A third category of mutants appeared to have a disturbance to the function of the aversive motivational system (P95 and P124).
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页码：73 / 79
页数：6
相关论文
共 16 条
[1]  
Kamyshev N.G., Iliadi K.G., Bragina Yu.V., Savvateeva-Popova E.V., Tokmacheva E.V., Preat R., Identification of mutant Drosophila with memory defects after acquisition of conditioned-reflex courtship suppression, Ros. Fiziol. Zh. Im. I. M. Sechenova, 85, 1, pp. 84-92, (1999)
[2]  
Kamyshev N.G., Iliadi K.G., Bragina J.V., Drosophila conditioned courtship. Two days of testing memory, Learning and Memory, 6, 1, pp. 1-20, (1999)
[3]  
Davis R.L., Physiology and biochemistry of Drosophila learning mutants, Physiol. Rev., 76, pp. 299-317, (1996)
[4]  
DiAntonio A., Learning something ORIGINal at the Drosophila neuromuscular junction, Neuron, 23, pp. 1-2, (1999)
[5]  
Dickinson A., Dearing M.F., Appetite-aversive interactions in inhibitory processes, Mechanisms of Learning and Motivation. A Memorial Volume to Jerzy Konorski, (1979)
[6]  
Dubnau J., Tully T., Gene discovery in Drosophila: New insights for learning and memory, Ann. Rev. Neurosci., 21, pp. 407-444, (1998)
[7]  
Gailey D.A., Jackson F.R., Siegel R.W., Male courtship in Drosophila. The conditioned response to immature males and its genetic control, Genetics, 102, pp. 771-782, (1982)
[8]  
Gailey D.A., Jackson F.R., Siegel R.W., Conditioning mutations in Drosophila melanogaster affect an experience-dependent behavioral modification in courting males, Genetics, 106, pp. 613-623, (1984)
[9]  
Hall J.C., The mating of a fly, Science, 264, pp. 1702-1714, (1994)
[10]  
Joiner M.A., Griffith L.C., CaM kinase II and visual input modulate memory formation in the neuronal circuit controlling courtship conditioning, J. Neurosci., 17, 23, pp. 9384-9391, (1997)
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