Herpes simplex virus and the alimentary tract

被引:31
作者
Lavery E.A. [1 ]
Coyle W.J. [1 ]
机构
[1] Division of Gastroenterology and Hepatology Scripps Clinic Torrey Pines, La Jolla, CA 92037
关键词
Herpes Simplex Virus; Esophagitis; Herpes Simplex Virus Type; Acyclovir; Achalasia;
D O I
10.1007/s11894-008-0078-8
中图分类号
学科分类号
摘要
Herpes simplex virus (HSV) infection is well known as a sexually transmitted disease. However, relatively little has been published concerning the presentations and treatment of HSV infection within the gastrointestinal tract, where HSV most commonly affects the esophagus in both immunocompromised and immunocompetent patients. HSV proctitis is not uncommon and occurs primarily in males having sex with males. In patients with normal immune systems, gastrointestinal HSV infections are generally self-limited and rarely require antiviral therapy. Treatment of infection is suggested for immunocompromised patients, though no large randomized controlled trials have been performed. This article reviews the manifestations of HSV infection within the luminal gastrointestinal tract and options for diagnosis and treatment. © Springer Science+Business Media, LLC 2008.
引用
收藏
页码:417 / 423
页数:6
相关论文
共 49 条
  • [1] Castagliuolo I., Brun P., Constantini M., Et al., Esophageal achalasia: Is the herpes simplex virus really innocent?, J Gastrointest Surg, 8, pp. 24-30, (2004)
  • [2] Fatahzadeh M., Schwartz R.A., Human herpes simplex virus infections: Epidemiology, pathogenesis, symptomatology, diagnosis, and management, J Am Acad Dermatol, 57, pp. 737-763, (2007)
  • [3] Steiner I., Kennedy P.G., Pachner A.R., The neurotropic herpes virus: Herpes simplex and varicella-zoster, Lancet, 6, pp. 1015-1028, (2007)
  • [4] Schacker T., Zeh J., Hu H., Et al., Frequency of symptomatic and asymptomatic herpes simplex virus type 2 reactivation among human immunodeficiency virus-infected men, J Infect Dis, 78, pp. 1616-1622, (1998)
  • [5] Drew W.L., Buhles W., Erlich K.S., Herpesvirus infections (cytomegalovirus, herpes simplex virus, varicella-zoster virus). How to use ganciclovir (DHPG) and acyclovir, Infect Dis Clin North Am, 2, pp. 495-509, (1988)
  • [6] Kato S., Yamamoto R., Yoshimitsu S., Et al., Herpes simplex esophagitis in the immunocompetent host, Dis Esophagus, 18, pp. 340-344, (2005)
  • [7] Galbraith J.C., Shafran S.D., Herpes simplex esophagitis in the immunocompetent patient: Report of four cases and review, Clin Infect Dis, 14, pp. 894-901, (1992)
  • [8] Ramanathan J., Rammouni M., Baran J., Khatib R., Herpes simplex virus esophagitis in the immunocompetent host: An overview, Am J Gastroenterol, 95, pp. 2171-2176, (2000)
  • [9] Cattan P., Cuillerier E., Cellier C., Et al., Black esophagus associated with herpes esophagitis, Gastrointest Endosc, 49, pp. 105-107, (1999)
  • [10] Fishbein P.G., Tuthill R., Kressel H., Et al., Herpes simplex esophagitis: A cause of upper-gastrointestinal bleeding, Dig Dis Sci, 24, pp. 540-544, (1979)