NLRP3 inhibition attenuates early brain injury and delayed cerebral vasospasm after subarachnoid hemorrhage

被引:0
作者
William S. Dodd
Imaray Noda
Melanie Martinez
Koji Hosaka
Brian L. Hoh
机构
[1] University of Florida,Department of Neurosurgery, College of Medicine
来源
Journal of Neuroinflammation | / 18卷
关键词
Subarachnoid hemorrhage; Microglia; NLRP3 inflammasome; Stroke; Inflammation;
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[1]  
Swanson KV(2019)The NLRP3 inflammasome: molecular activation and regulation to therapeutics Nat Rev Immunol 19 477-489
[2]  
Deng M(2018)The pathological role of NLRs and AIM2 inflammasome-mediated pyroptosis in damaged blood-brain barrier after traumatic brain injury Brain Res 1697 10-20
[3]  
Ting JPY(2020)Inhibition of AIM2 inflammasome activation alleviates GSDMD-induced pyroptosis in early brain injury after subarachnoid haemorrhage Cell Death Dis 11 76-603
[4]  
Ge X(2020)Inhibition of double-strand DNA-sensing cGAS ameliorates brain injury after ischemic stroke EMBO Mol Med 12 e11002-8
[5]  
Li W(2018)The NLRP3 inflammasome: an important driver of neuroinflammation in hemorrhagic stroke Cell Mol Neurobiol 38 595-800
[6]  
Huang S(2018)NLRP3: a novel mediator in cardiovascular disease J Immunol Res 2018 1-221
[7]  
Yin Z(2016)Inflammasome complexes: emerging mechanisms and effector functions Cell 165 792-340
[8]  
Xu X(2000)The detection and management of unruptured intracranial aneurysms Brain 123 205-182
[9]  
Chen F(2018)Predictors of in-hospital death after aneurysmal subarachnoid hemorrhage: analysis of a nationwide database (Swiss SOS [Swiss Study on Aneurysmal Subarachnoid Hemorrhage]) Stroke 49 333-472
[10]  
Kong X(2016)The pathophysiology of delayed cerebral ischemia J Clin Neurophysiol 33 174-3019