Substrate Specificity of Na+,Cl–(HCO3–)-ATPase

被引：0
作者：
V. A. Yurkiv
V. I. Melikhov
V. S. Shubin
机构：
[1] Russian Academy of Sciences,Research Institute of General Pathology and Pathological Physiology
来源：
Bulletin of Experimental Biology and Medicine | 2016年 / 161卷
关键词：
secretory process; small intestine; Na; ,Cl; (HCO; )-ATPase; CFTR protein;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We studied substrate specificity of Na+,Cl–(HCO3–)-ATPase. In most cases, replacement of ATP for other phosphate-containing substances resulted in not only pronounced suppression of phosphohydrolase reactions, but also dramatic changes of their responsiveness to the stimulating effect of monovalent ions. The data showed that Na+,Cl–(HCO3–)-ATPase is a highly specific enzyme for ATP.
引用
收藏
页码：651 / 653
页数：2
相关论文
共 50 条
  • [11] Effects of GABAA-ergic ligands on Cl− transport induced by the Cl−, HCO3−-ATPase from carp (Cyprinus carpio L.) brain reconstituted in proteoliposomes
    S. A. Menzikov
    O. V. Menzikova
    Neurochemical Journal, 2007, 1 : 31 - 36
  • [12] Regulation of Renal Na+/HCO3− Cotransporter Stimulation by CO2: Role of Phosphorylation, Exocytosis and Protein Synthesis
    D.J.D. Espiritu
    V.L. Yang
    A.A. Bernardo
    J.A.L. Arruda
    The Journal of Membrane Biology, 2004, 199 : 39 - 49
  • [13] Cl--dependent and Cl--independent Na+/HCO3- acid extrusion in cultured rat cerebellar astrocytes
    Ko, YP
    Lang, HJ
    Loh, SH
    Chu, KC
    Wu, ML
    CHINESE JOURNAL OF PHYSIOLOGY, 1999, 42 (04): : 237 - 248
  • [14] Molecular Weight and Subunit Composition of the Sensitive to GABA-Ergic Ligands Cl−/HCO3−-Stimulated Mg2+-ATPase from Plasma Membrane of Rat Brain
    S. A. Menzikov
    O. V. Menzikova
    Biochemistry (Moscow), 2005, 70 : 1385 - 1389
  • [15] MODULATION OF NA+, CL- AND HCO3- TRANSPORT BY CARBACHOL IN PIG DISTAL JEJUNUM
    CHANDAN, R
    OGRADY, SM
    BROWN, DR
    EUROPEAN JOURNAL OF PHARMACOLOGY, 1991, 193 (03) : 257 - 264
  • [16] Intracellular Cl- as a signaling ion that potently regulates Na+/HCO3- transporters
    Shcheynikov, Nikolay
    Son, Aran
    Hong, Jeong Hee
    Yamazaki, Osamu
    Ohana, Ehud
    Kurtz, Ira
    Shin, Dong Min
    Muallem, Shmuel
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2015, 112 (03) : E329 - E337
  • [17] Secretin stimulates HCO3- and acetate efflux but not Na+/HCO3- uptake in rat pancreatic ducts
    Novak, I
    Christoffersen, BC
    PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2001, 441 (06): : 761 - 771
  • [18] Comparative properties of sensitive to GABAA-ergic ligands Cl−, HCO3−-activated Mg2+-ATPase from brain plasma membranes of fish and rats
    S. A. Menzikov
    O. V. Menzikova
    Journal of Evolutionary Biochemistry and Physiology, 2007, 43 : 295 - 304
  • [19] Na+,K+-ATPase as a docking station: protein–protein complexes of the Na+,K+-ATPase
    Linda Reinhard
    Henning Tidow
    Michael J. Clausen
    Poul Nissen
    Cellular and Molecular Life Sciences, 2013, 70 : 205 - 222
  • [20] Role of cholesterol in functional association between K+-Cl- cotransporter-3a and Na+,K+-ATPase
    Fujita, Kyosuke
    Fujii, Takuto
    Shimizu, Takahiro
    Takeguchi, Noriaki
    Sakai, Hideki
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2012, 424 (01) : 136 - 140
12345