Substrate Specificity of Na+,Cl–(HCO3–)-ATPase

被引:0
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作者
V. A. Yurkiv
V. I. Melikhov
V. S. Shubin
机构
[1] Russian Academy of Sciences,Research Institute of General Pathology and Pathological Physiology
关键词
secretory process; small intestine; Na; ,Cl; (HCO; )-ATPase; CFTR protein;
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摘要
We studied substrate specificity of Na+,Cl–(HCO3–)-ATPase. In most cases, replacement of ATP for other phosphate-containing substances resulted in not only pronounced suppression of phosphohydrolase reactions, but also dramatic changes of their responsiveness to the stimulating effect of monovalent ions. The data showed that Na+,Cl–(HCO3–)-ATPase is a highly specific enzyme for ATP.
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页码:651 / 653
页数:2
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