DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies

被引：0

作者：

Florianne O. L. Vehmeijer

Leanne K. Küpers

Gemma C. Sharp

Lucas A. Salas

Samantha Lent

Dereje D. Jima

Gwen Tindula

Sarah Reese

Cancan Qi

Olena Gruzieva

Christian Page

Faisal I. Rezwan

Philip E. Melton

Ellen Nohr

Geòrgia Escaramís

Peter Rzehak

Anni Heiskala

Tong Gong

Samuli T. Tuominen

Lu Gao

Jason P. Ross

Anne P. Starling

John W. Holloway

Paul Yousefi

Gunn Marit Aasvang

Lawrence J. Beilin

Anna Bergström

Elisabeth Binder

Leda Chatzi

Eva Corpeleijn

Darina Czamara

Brenda Eskenazi

Susan Ewart

Natalia Ferre

Veit Grote

Dariusz Gruszfeld

Siri E. Håberg

Cathrine Hoyo

Karen Huen

Robert Karlsson

Inger Kull

Jean-Paul Langhendries

Johanna Lepeule

Maria C. Magnus

Rachel L. Maguire

Peter L. Molloy

Claire Monnereau

Trevor A. Mori

Emily Oken

Katri Räikkönen

机构：

[1] University Medical Center Rotterdam,The Generation R Study Group, Erasmus MC

[2] University Medical Center Rotterdam,Department of Pediatrics, Erasmus MC

[3] University Medical Center Rotterdam,Department of Epidemiology, Erasmus MC

[4] University of Bristol,MRC Integrative Epidemiology Unit

[5] University of Bristol,Population Health Sciences, Bristol Medical School

[6] University of Groningen,Department of Biostatistics

[7] University Medical Center Groningen,Bioinformatics Research Center

[8] Department of Epidemiology,Center for Human Health and the Environment

[9] Geisel School of Medicine at Dartmouth,Children’s Environmental Health Laboratory, Division of Environmental Health Sciences, School of Public Health

[10] ISGlobal,Department of Health and Human Services

[11] Universitat Pompeu Fabra (UPF),University Medical Center Groningen GRIAC Research Institute

[12] CIBER of Epidemiology and Public Health (CIBERESP),Institute of Environmental Medicine

[13] Boston University School of Public Health,Centre for Occupational and Environmental Medicine

[14] North Carolina State University,Centre for Fertility and Health

[15] North Carolina State University,Oslo Centre for Biostatistics and Epidemiology

[16] University of California,School of Water, Energy and Environment

[17] Epidemiology Branch,Human Development and Health, Faculty of Medicine, Southampton General Hospital

[18] National Institute of Environmental Health Sciences,School of Pharmacy and Biomedical Sciences

[19] National Institutes of Health,School of Biomedical Sciences

[20] University of Groningen,Centre for Women’s, Family and Child Health

[21] University Medical Center Groningen,Institute of Clinical Research

[22] Department of Pediatric Pulmonology and Pediatric Allergy,Department of Biomedical Sciences, Faculty of Medicine and Health Sciences

[23] Beatrix Children’s Hospital,Research group on Statistics, Econometrics and Health (GRECS)

[24] University of Groningen,Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children’s Hospital

[25] Karolinska Institutet,Center for Life Course Health Research

[26] Region Stockholm,Department of Medical Epidemiology and Biostatistics

[27] Norwegian Institute of Public Health,Department of Psychology and Logopedics, Faculty of Medicine

[28] Oslo University Hospital,Department of Preventive Medicine

[29] Cranfield University,Department of Epidemiology

[30] University of Southampton,Lifecourse Epidemiology of Adiposity and Diabetes (LEAD) Center

[31] Curtin University,Clinical and Experimental Sciences, Faculty of Medicine

[32] The University of Western Australia,Department of Air Pollution and Noise

[33] University of South-Eastern Norway,Medical School

[34] University of Southern Denmark,Department of Translational Research in Psychiatry

[35] University of Barcelona,Department of Psychiatry and Behavioral Sciences

[36] University of Girona,Department of Preventive Medicine, Keck School of Medicine

[37] Ludwig-Maximilians Universität München (LMU),Center for Environmental Research and Children’s Health, School of Public Health

[38] University of Oulu,College of Veterinary Medicine

[39] Karolinska Institutet,Pediatrics, Nutrition and Development Research Unit

[40] University of Helsinki,Department of Biological Sciences

[41] University of Southern California,Department of Clinical Science and Education, Södersjukhuset

[42] CSIRO Health and Biosecurity,Sachs’ Children and Youth Hospital

[43] Colorado School of Public Health,Department of Obstetrics and Gynecology

[44] University of Colorado Anschutz Medical Campus,Department of Population Medicine, Harvard Medical School

[45] University of Southampton,Department of Pediatrics, San Paolo Hospital

[46] Norwegian Institute of Public Health,Division of Biomedical Informatics and Personalized Medicine, Department of Medicine

[47] University of Western Australia,Center for Genes, Environment and Health

[48] Max-Planck-Institute of Psychiatry,Division of Epidemiology, Biostatistics, and Environmental Health

[49] Emory University School of Medicine,Department of Biostatistics and Informatics

[50] University of Southern California,Department of Pediatrics, School of Medicine

来源：

Genome Medicine | / 12卷

关键词：

Body mass index; Childhood obesity; DNA methylation; Epigenetics;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 371 条

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[2]

Stewart AW(2019)Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight Nat Commun 10 1893-1198

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Monnereau C(2015)Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci Hum Mol Genet 24 4464-35

[9]

Sharp GC(2017)Association of body mass index with DNA methylation and gene expression in blood cells and relations to cardiometabolic disease: a Mendelian randomization approach Plos Med 14 e1002215-1005

[10]

Yousefi P(2015)Genome-wide screen of DNA methylation identifies novel markers in childhood obesity Gene. 566 74-1534

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