Harnessing programmed cell death as a therapeutic strategy in rheumatic diseases

被引:0
|
作者
Madhu Ramaswamy
Min Deng
Richard M. Siegel
机构
[1] Immunoregulation Section,
[2] Autoimmunity Branch,undefined
[3] National Institute of Arthritis and Musculoskeletal and Skin Diseases,undefined
[4] NIH,undefined
来源
Nature Reviews Rheumatology | 2011年 / 7卷
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摘要
Programmed cell death (PCD) is a vital process in the development and maintenance of immune cell populations. In this Review, the authors describe some of the major mechanisms of apoptosis, the role of defective PCD in autoimmunity, and the potential of therapeutic targeting of apoptosis pathways in patients with rheumatic diseases.
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页码:152 / 160
页数:8
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