Targeting sphingolipid metabolism with the sphingosine kinase inhibitor SKI-II overcomes hypoxia-induced chemotherapy resistance in glioblastoma cells: effects on cell death, self-renewal, and invasion

被引：0

作者：

Nadia Sousa

Carsten Geiß

Laura Bindila

Ingo Lieberwirth

Ella Kim

Anne Régnier-Vigouroux

机构：

[1] Johannes Gutenberg University Mainz,Institute of Developmental Biology & Neurobiology

[2] Institute of Physiological Chemistry,Clinical Lipidomics Unit

[3] Medical University Mainz,Department of Neurosurgery

[4] Max Planck Institute for Polymer Research,undefined

[5] Medical University of Mainz,undefined

来源：

关键词：

Hypoxia; Glioblastoma therapy; Drug combination; Temozolomide; SKI-II; Sphingolipids; Invasion; Glioblastoma stem cells; Cell death;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用