CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism

[41] Thomas LW(2018)NADH shuttling couples cytosolic reductive carboxylation of glutamine with glycolysis in cells with mitochondrial dysfunction Mol Cell 69 581-197

[42] Thomas LW(2009)Reduced proliferation and enhanced migration: two sides of the same coin? Molecular mechanisms of metastatic progression by YB-1 Cell Cycle 8 2901-292

[43] Fischer M(2003)Invade or proliferate? Two contrasting events in malignant behavior governed by p16(INK4a) and an intact Rb pathway illustrated by a model system of basal cell carcinoma Cancer Res 63 1737-46

[44] Modjtahedi N(2014)To “grow” or “go”: TMEM16A expression as a switch between tumor growth and metastasis in SCCHN Clin Cancer Res 20 4673-129

[45] Kroemer G(2010)Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition FASEB J 24 1838-503

[46] Hangen E(2015)Real-time analysis of epithelial-mesenchymal transition using fluorescent single-domain antibodies Sci Rep 5 13402-529

[47] Blacker TS(2013)TGF-beta1 exposure induces epithelial to mesenchymal transition both in CSCs and non-CSCs of the A549 cell line, leading to an increase of migration ability in the CD133+ A549 cell fraction Cell Death Dis 4 e620-547

[48] Duchen MR(2012)MYC on the path to cancer Cell 149 22-721

[49] Saxton RA(2008)The interplay between MYC and HIF in cancer Nat Rev Cancer 8 51-408

[50] Sabatini DM(2016)Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival Nat Commun 7 13041-123

[41] Thomas LW(2018)NADH shuttling couples cytosolic reductive carboxylation of glutamine with glycolysis in cells with mitochondrial dysfunction Mol Cell 69 581-197

[42] Thomas LW(2009)Reduced proliferation and enhanced migration: two sides of the same coin? Molecular mechanisms of metastatic progression by YB-1 Cell Cycle 8 2901-292

[43] Fischer M(2003)Invade or proliferate? Two contrasting events in malignant behavior governed by p16(INK4a) and an intact Rb pathway illustrated by a model system of basal cell carcinoma Cancer Res 63 1737-46

[44] Modjtahedi N(2014)To “grow” or “go”: TMEM16A expression as a switch between tumor growth and metastasis in SCCHN Clin Cancer Res 20 4673-129

[45] Kroemer G(2010)Vimentin induces changes in cell shape, motility, and adhesion during the epithelial to mesenchymal transition FASEB J 24 1838-503

[46] Hangen E(2015)Real-time analysis of epithelial-mesenchymal transition using fluorescent single-domain antibodies Sci Rep 5 13402-529

[47] Blacker TS(2013)TGF-beta1 exposure induces epithelial to mesenchymal transition both in CSCs and non-CSCs of the A549 cell line, leading to an increase of migration ability in the CD133+ A549 cell fraction Cell Death Dis 4 e620-547

[48] Duchen MR(2012)MYC on the path to cancer Cell 149 22-721

[49] Saxton RA(2008)The interplay between MYC and HIF in cancer Nat Rev Cancer 8 51-408

[50] Sabatini DM(2016)Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival Nat Commun 7 13041-123