Induction of CD4+CD25+FOXP3+ regulatory T cells by mesenchymal stem cells is associated with modulation of ubiquitination factors and TSDR demethylation

[1] Amsen D(2004)Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells Cell 117 515-526

[2] Blander JM(2015)Ubiquitin-dependent regulation of Foxp3 and Treg function Immunol Rev 266 27-45

[3] Lee GR(2011)Mesenchymal stem cells as an immunomodulatory therapeutic strategy for autoimmune diseases Autoimmun Rev 10 410-415

[4] Tanigaki K(2008)Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study Lancet 371 1579-1586

[5] Honjo T(2015)Jagged-1 is required for the expansion of CD4+CD25+FoxP3+ regulatory T cells and tolerogenic dendritic cells by murine mesenchymal stromal cells Stem Cell Res Ther 6 19-3946

[6] Flavell RA(2008)Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory T cells J Immunol 181 3933-253

[7] Barbi J(2016)Mesenchymal stromal cells in renal transplantation: opportunities and challenges Nat Rev Nephrol 12 241-4757

[8] Pardoll DM(2010)TRAF6 inhibits Th17 differentiation and TGF-β-mediated suppression of IL-2 Blood 115 4750-352

[9] Pan F(2013)Ubiquitination signals critical to regulatory T cell development and function Int Immunopharmacol 16 348-285

[10] Ben-Ami E(2013)The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3 Immunity 39 272-1333

[1] Amsen D(2004)Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells Cell 117 515-526

[2] Blander JM(2015)Ubiquitin-dependent regulation of Foxp3 and Treg function Immunol Rev 266 27-45

[3] Lee GR(2011)Mesenchymal stem cells as an immunomodulatory therapeutic strategy for autoimmune diseases Autoimmun Rev 10 410-415

[4] Tanigaki K(2008)Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study Lancet 371 1579-1586

[5] Honjo T(2015)Jagged-1 is required for the expansion of CD4+CD25+FoxP3+ regulatory T cells and tolerogenic dendritic cells by murine mesenchymal stromal cells Stem Cell Res Ther 6 19-3946

[6] Flavell RA(2008)Pretransplant infusion of mesenchymal stem cells prolongs the survival of a semiallogeneic heart transplant through the generation of regulatory T cells J Immunol 181 3933-253

[7] Barbi J(2016)Mesenchymal stromal cells in renal transplantation: opportunities and challenges Nat Rev Nephrol 12 241-4757

[8] Pardoll DM(2010)TRAF6 inhibits Th17 differentiation and TGF-β-mediated suppression of IL-2 Blood 115 4750-352

[9] Pan F(2013)Ubiquitination signals critical to regulatory T cell development and function Int Immunopharmacol 16 348-285

[10] Ben-Ami E(2013)The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3 Immunity 39 272-1333