A survey of attitudes, practices, and knowledge regarding drug–drug interactions among medical residents in Iran

被引:0
作者
Ehsan Nabovati
Hasan Vakili-Arki
Zhila Taherzadeh
Mohammad Reza Saberi
Ameen Abu-Hanna
Saeid Eslami
机构
[1] Kashan University of Medical Sciences,Health Information Management Research Center
[2] Kashan University of Medical Sciences,Department of Health Information Management and Technology, School of Allied Health Professions
[3] Mashhad University of Medical Sciences,Student Research Committee, Department of Medical Informatics, Faculty of Medicine
[4] Mashhad University of Medical Sciences,Targeted Drug Delivery Research Center
[5] Mashhad University of Medical Sciences,Neurogenic Inflammation Research Center
[6] Mashhad University of Medical Sciences,Medical Chemistry Department, School of Pharmacy
[7] Mashhad University of Medical Sciences,Pharmaceutical Research Center, School of Pharmacy
[8] Mashhad University of Medical Sciences,Department of Medical Informatics, Faculty of Medicine
[9] University of Amsterdam,Department of Medical Informatics, Academic Medical Center
来源
International Journal of Clinical Pharmacy | 2017年 / 39卷
关键词
Drug–drug interaction; Information sources; Iran; Medication knowledge; Performance feedback; Prescribers’ attitude;
D O I
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中图分类号
学科分类号
摘要
Background When prescribing medications, physicians should recognize clinically relevant potential drug–drug interactions (DDIs). To improve medication safety, it is important to understand prescribers’ knowledge and opinions pertaining to DDIs. Objective To determine the current DDI information sources used by medical residents, their knowledge of DDIs, their opinions about performance feedback on co-prescription of interacting drugs. Setting Academic hospitals of Mashhad University of Medical Sciences (MUMS) in Iran. Methods A questionnaire containing questions regarding demographic and practice characteristics, DDI information sources, ability to recognize DDIs, and opinions about performance feedback was distributed to medical residents of 22 specialties in eight academic hospitals in Iran. We analyzed their perception pertaining to DDIs, their performance on classifying drug pairs, and we used a linear regression model to assess the association of potential determinants on their DDI knowledge. Main Outcome Measure prescribers’ knowledge and opinions pertaining to DDIs. Results The overall response rate and completion rate for 315 distributed questionnaires were 90% (n = 295) and 86% (n = 281), respectively. Among DDI information sources, books, software on mobile phone or tablet, and Internet were the most commonly-used references. Residents could correctly classify only 41% (5.7/14) of the drug pairs. The regression model showed no significant association between residents’ characteristics and their DDI knowledge. An overwhelming majority of the respondents (n = 268, 95.4%) wished to receive performance feedback on co-prescription of interacting drugs in their prescriptions. They mostly selected information technology-based tools (i.e. short text message and email) as their preferred method of receiving feedback. Conclusion Our findings indicate that prescribers may have poor ability to prevent clinically relevant potential DDI occurrence, and they perceive the need for performance feedback. These findings underline the importance of well-designed computerized alerting systems and delivering performance feedback to improve patient safety.
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页码:560 / 568
页数:8
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共 181 条
[21]  
Dupont AG(2007)Confounder selection in environmental epidemiology: assessment of health effects of prenatal mercury exposure Ann Epidemiol 17 27-177
[22]  
Malone DC(2007)Practitioners’ views on computerized drug–drug interaction alerts in the VA system J Am Med Inform Assoc JAMIA. 14 56-486
[23]  
Liberman JN(2011)The role of clinical pharmacists in educating nurses to reduce drug–food interactions (absorption phase) in hospitalized patients Iran J Pharm Res IJPR. 10 173-284
[24]  
Sun D(2013)Detection and management of medication errors in internal wards of a teaching hospital by clinical pharmacists Acta Medica Iranica. 51 482-233
[25]  
Bista D(2011)Role of clinical pharmacists’ interventions in detection and prevention of medication errors in a medical ward Int J Clin Pharm. 33 281-436
[26]  
Saha A(2013)Evaluation of clinical pharmacist’s interventions in an infectious diseases ward and impact on patient’s direct medication cost Eur J Intern Med. 24 227-129
[27]  
Mishra P(2009)Prevalence of polypharmacy, polyherbacy, nutritional supplement use and potential product interactions among older adults living on the United States–Mexico border: a descriptive, questionnaire-based study Drugs Aging 26 423-499
[28]  
Palaian S(2006)Herbal, prescribed, and over-the-counter drug use in older women: prevalence of drug interactions Geriatr Nursing 27 118-2878
[29]  
Shankar PR(2000)Frequency of daily over-the-counter drug use and potential clinically significant over-the-counter-prescription drug interactions in the Finnish adult population Eur J Clin Pharmacol 56 495-540
[30]  
Andersson ML(2008)Use of prescription and over-the-counter medications and dietary supplements among older adults in the United States JAMA 300 2867-151