A Coumarin-Based Fluorescent Probe for Selective Detection of Cu(II) and Imaging in Human Cell

被引：2

作者：

Gao, Shan ^{[1
]}

Wang, Ai-Ling ^{[2
]}

Wang, Ming-Zhe ^{[1
]}

机构：

[1] Liaoning Normal Univ, Inst Phys Educ, Dalian 116029, Peoples R China

[2] Dalian Univ, Coll Environm & Chem Engn, Dalian 116622, Peoples R China

来源：

RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2024年 / 60卷 / 03期

基金：

中国国家自然科学基金;

关键词：

Schiff base; fluorescent probe; detection; Cu(II) ions; CHEMOSENSOR; CU2+; COPPER; IONS; MECHANISMS;

D O I：

10.1134/S107042802403014X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel coumarin-derived Schiff base fluorescent probe was reported to detect Cu2+ ions in human cells. It was synthesized by the reaction between 7-(diethylamino)coumarin-3-carbohydrazide and pyridoxal 5 '-phosphate. The probe has good stability and it exhibited obviously decreasing fluorescent response at lambda 490 nm upon addition of Cu(II) ions. The fluorescent probe showed high selectivity for Cu(II) ions compared to other metal ions. The probe has been successfully applied to detect Cu(II) ions in human cells.

引用

页码：467 / 471

页数：5

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