Total neoadjuvant FOLFIRINOX versus neoadjuvant gemcitabine-based chemoradiotherapy and adjuvant gemcitabine for resectable and borderline resectable pancreatic cancer (PREOPANC-2 trial): study protocol for a nationwide multicenter randomized controlled trial

被引：0

作者：

Q. P. Janssen

J. L. van Dam

B. A. Bonsing

H. Bos

K. P. Bosscha

P. P. L. O. Coene

C. H. J. van Eijck

I. H. J. T. de Hingh

T. M. Karsten

M. B. van der Kolk

G. A. Patijn

M. S. L. Liem

H. C. van Santvoort

O. J. L. Loosveld

J. de Vos-Geelen

B. M. Zonderhuis

M. Y. V. Homs

G. van Tienhoven

M. G. Besselink

J. W. Wilmink

B. Groot Koerkamp

机构：

[1] Erasmus MC University Medical Center,Department of Surgery

[2] Leiden University Medical Center,Department of Surgery

[3] Tjongerschans Hospital,Department of Medical Oncology

[4] Jeroen Bosch Hospital,Department of Surgery

[5] Maasstad Hospital,Department of Surgery

[6] Catharina Hospital,Department of Surgery

[7] Department of Surgery,Department of Surgery

[8] Onze Lieve Vrouwe Gasthuis,Department of Surgery

[9] Radboud University Medical Center,Department of Surgery, Regional Academic Cancer Center Utrecht

[10] Isala Hospital,Department of Medical Oncology

[11] Department of Surgery,Department of Internal Medicine, Division of Medical Oncology

[12] Medisch Spectrum Twente,Department of Surgery, Cancer Center Amsterdam

[13] St. Antonius Hospital and University Medical Center Utrecht,Department of Medical Oncology

[14] Amphia Hospital,Department of Radiation Oncology, Cancer Center Amsterdam

[15] GROW - School for Oncology and Developmental Biology,Department of Surgery, Cancer Center Amsterdam

[16] Maastricht UMC+,Department of Medical Oncology, Cancer Center Amsterdam

[17] Amsterdam UMC,undefined

[18] Vrije Universiteit,undefined

[19] Erasmus MC University Medical Center,undefined

[20] Amsterdam UMC,undefined

[21] University of Amsterdam,undefined

[22] Amsterdam UMC,undefined

[23] University of Amsterdam,undefined

[24] Amsterdam UMC,undefined

[25] University of Amsterdam,undefined

来源：

BMC Cancer | / 21卷

关键词：

Neoadjuvant; FOLFIRINOX; Gemcitabine; Chemoradiotherapy; Localized pancreatic cancer; Intention-to-treat; Randomized controlled trial; Overall survival; Quality of life;

D O I：

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引用

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