Dl-3-n-Butylphthalide improves lipopolysaccharide-induced depressive-like behavior in rats: involvement of Nrf2 and NF-κB pathways

被引:0
作者
Mengqi Yang
Ruili Dang
Pengfei Xu
Yujin Guo
Wenxiu Han
Dehua Liao
Pei Jiang
机构
[1] Jining Medical University,Institute of Clinical Pharmacy & Pharmacology, Jining First People’s Hospital
[2] Central South University,Department of Pharmacy, Hunan Cancer Hospital
来源
Psychopharmacology | 2018年 / 235卷
关键词
Major depressive disorder; Dl-3-n-butylphthalide; Inflammation; Nrf2 signaling;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:2573 / 2585
页数:12
相关论文
共 223 条
[1]  
Abdoulaye IA(2016)A review of recent advances in neuroprotective potential of 3-N-butylphthalide and its derivatives Biomed Res Int 2016 1-9
[2]  
Yi JG(2015)The contribution of hypothalamic neuroendocrine, neuroplastic and neuroinflammatory processes to lipopolysaccharide-induced depressive-like behaviour in female and male rats: involvement of glucocorticoid receptor and C/EBP-β Behav Brain Res 291 130-139
[3]  
Adzic M(2003)Effects of chiral 3-n-butylphthalide on apoptosis induced by transient focal cerebral ischemia in rats Acta Pharmacol Sin 24 796-804
[4]  
Djordjevic J(2014)The plasma levels of various cytokines are increased during ongoing depression and are reduced to normal levels after recovery Psychoneuroendocrinology 45 77-86
[5]  
Mitic M(2017)Fish oil supplementation attenuates neuroinflammation and alleviates depressive-like behavior in rats submitted to repeated lipopolysaccharide Eur J Nutr 57 893-906
[6]  
Brkic Z(2017)ω-3 polyunsaturated fatty acid supplementation ameliorates lipopolysaccharide-induced behavioral deficits and modulates neurotrophic factors in rats: focus on tPA/PAI-1 system and BDNF-TrkB signaling J Funct Foods 30 74-80
[7]  
Lukic I(2002)Endotoxin, but not platelet-activating factor, activates nuclear factor-kappaB and increases IkappaBalpha and IkappaBbeta turnover in enterocytes Immunology 106 577-583
[8]  
Radojcic M(2013)Metabolism and pharmacokinetics of 3-n-butylphthalide (NBP) in humans: the role of cytochrome P450s and alcohol dehydrogenase in biotransformation Drug Metab Dispos 41 430-444
[9]  
Chang Q(2015)Isomer-selective distribution of 3-n-butylphthalide (NBP) hydroxylated metabolites, 3-hydroxy-NBP and 10-hydroxy-NBP, across the rat blood-brain barrier Acta Pharmacol Sin 36 1520-1527
[10]  
Wang XL(2016)Interleukin-1 β-targeted treatment strategies in inflammatory depression: toward personalized care Acta Psychiatr Scand 134 469-484