Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups

被引：0

作者：

Mustapha Abubakar

Nick Orr

Frances Daley

Penny Coulson

H. Raza Ali

Fiona Blows

Javier Benitez

Roger Milne

Herman Brenner

Christa Stegmaier

Arto Mannermaa

Jenny Chang-Claude

Anja Rudolph

Peter Sinn

Fergus J. Couch

Peter Devilee

Rob A. E. M. Tollenaar

Caroline Seynaeve

Jonine Figueroa

Mark E. Sherman

Jolanta Lissowska

Stephen Hewitt

Diana Eccles

Maartje J. Hooning

Antoinette Hollestelle

John W. M. Martens

Carolien H. M. van Deurzen

kConFab Investigators

Manjeet K. Bolla

Qin Wang

Michael Jones

Minouk Schoemaker

Jelle Wesseling

Flora E. van Leeuwen

Laura Van ‘t Veer

Douglas Easton

Anthony J. Swerdlow

Mitch Dowsett

Paul D. Pharoah

Marjanka K. Schmidt

Montserrat Garcia-Closas

机构：

[1] The Institute of Cancer Research,Division of Genetics and Epidemiology

[2] The Institute of Cancer Research,Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer Research

[3] Cancer Research UK Cambridge Institute,Centre for Cancer Genetic Epidemiology, Department of Oncology

[4] University of Cambridge,Human Genetics Group, Human Cancer Genetics Program

[5] University of Cambridge,Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global health

[6] Spanish National Cancer Research Centre (CNIO),Division of Clinical Epidemiology and Aging Research

[7] Centro de Investigacion en Red de Enfermedades Raras (CIBERER),Division of Preventive Oncology

[8] Cancer Epidemiology Centre,School of Medicine, Institute of Clinical Medicine, Pathology and Forensic Medicine, Cancer Center of Eastern Finland

[9] Cancer Council Victoria,Imaging Center, Department of Clinical Pathology

[10] The University of Melbourne,Division of Cancer Epidemiology

[11] German Cancer Research Center (DKFZ),Department of Pathology, Institute of Pathology

[12] German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT),Department of Laboratory Medicine and Pathology

[13] German Cancer Consortium (DKTK),Department of Human Genetics and Department of Pathology

[14] German Cancer Research Center (DKFZ),Department of Surgery

[15] Saarland Cancer Registry,Department of Medical Oncology, Family Cancer Clinic

[16] University of Eastern Finland,Usher Institute of Population Health Sciences and Informatics

[17] Kuopio University Hospital,Divisions of Cancer Epidemiology and Genetics

[18] German Cancer Research Center (DKFZ),Department of Cancer Epidemiology and Prevention

[19] University Cancer Center Hamburg,Faculty of Medicine Academic Unit of Cancer Sciences

[20] University Medical Center Hamburg-Eppendorf,Family Cancer Clinic, Department of Medical Oncology

[21] Heidelberg University Hospital,Department of Pathology

[22] Mayo Clinic,Department of Genetics

[23] Leiden University Medical Center,Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care

[24] Leiden University Medical Center,Division of Molecular Pathology

[25] Erasmus MC Cancer Institute,Division of Psychosocial Research and Epidemiology

[26] The University of Edinburgh,Division of Breast Cancer Research

[27] National Cancer Institute,Academic Department of Biochemistry

[28] M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology,undefined

[29] Laboratory of Pathology,undefined

[30] National Cancer Institute,undefined

[31] National Institutes of Health,undefined

[32] Southampton General Hospital,undefined

[33] Erasmus MC Cancer Institute,undefined

[34] Erasmus MC Cancer Institute,undefined

[35] QIMR Berghofer Medical Research Institute,undefined

[36] University of Cambridge,undefined

[37] Netherlands Cancer Institute,undefined

[38] Antoni van Leeuwenhoek Hospital,undefined

[39] Netherlands Cancer Institute,undefined

[40] Antoni van Leeuwenhoek Hospital,undefined

[41] The Institute of Cancer Research,undefined

[42] Royal Marsden Hospital,undefined

来源：

Breast Cancer Research | / 18卷

关键词：

Breast cancer; Automated KI67; Visual KI67; Prognostication;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 50 条

[1] Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups
Abubakar, Mustapha
Orr, Nick
Daley, Frances
Coulson, Penny
Ali, H. Raza
Blows, Fiona
Benitez, Javier
Milne, Roger
Brenner, Herman
Stegmaier, Christa
Mannermaa, Arto
Chang-Claude, Jenny
Rudolph, Anja
Sinn, Peter
Couch, Fergus J.
Devilee, Peter
Tollenaar, Rob A. E. M.
Seynaeve, Caroline
Figueroa, Jonine
Sherman, Mark E.
Lissowska, Jolanta
Hewitt, Stephen
Eccles, Diana
Hooning, Maartje J.
Hollestelle, Antoinette
Martens, John W. M.
van Deurzen, Carolien H. M.
Bolla, Manjeet K.
Wang, Qin
Jones, Michael
Schoemaker, Minouk
Wesseling, Jelle
van Leeuwen, Flora E.
Van 't Veer, Laura
Easton, Douglas
Swerdlow, Anthony J.
Dowsett, Mitch
Pharoah, Paul D.
Schmidt, Marjanka K.
Garcia-Closas, Montserrat
BREAST CANCER RESEARCH, 2016, 18
[2] The Ki67 dilemma: investigating prognostic cut-offs and reproducibility for automated Ki67 scoring in breast cancer
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[3] Automated computational Ki67 scoring in the GeparTrio breast cancer study cohort
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von Minckwitz, G.
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[4] Independent Clinical Validation of the Automated Ki67 Scoring Guideline from the International Ki67 in Breast Cancer Working Group
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BIOMOLECULES, 2021, 11 (11)
[5] Prognostic Significance of the Ki67 Scoring Categories in Breast Cancer Subgroups
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CLINICAL BREAST CANCER, 2014, 14 (05) : 323 - 329
[6] An international multicenter study to evaluate reproducibility of automated scoring for assessment of Ki67 in breast cancer
Rimm, David L.
Leung, Samuel C. Y.
McShane, Lisa M.
Bai, Yalai
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MODERN PATHOLOGY, 2019, 32 (01) : 59 - 69
[7] Analytical validation and prognostic potential of an automated digital scoring protocol for Ki67: An International Ki67 Working Group study
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Leung, Samuel C. Y.
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Badve, Sunil S.
Bai, Yalai
Bane, Anita L.
Bartlett, John M. S.
Bayani, Jane
Bigras, Gilbert
Blank, Annika
Borgquist, Signe
Buikema, Henk
Chang, Martin C.
Dietz, Robin L.
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Ehinger, Anna
Fineberg, Susan
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Hartman, Johan
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Kos, Zuzana
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Penault-Llorca, Frederique M.
Piper, Tammy
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Rau, Tilman T.
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CANCER RESEARCH, 2020, 80 (04)
[8] Prognostic value of Ki67 labelling index in invasive breast cancer
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ONKOLOGIE, 2013, 36 : 175 - 176
[9] An international multicenter study to evaluate reproducibility of automated scoring methods for assessment of Ki67 in breast cancer
Rimm, D. L.
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Leung, S. C. Y.
Bai, Y.
Bane, A. L.
Bartlett, J. M. S.
Bayani, J.
Chang, M. C.
Dean, M.
Denkert, C.
Enwere, E.
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Gholap, A.
Hugh, J. C.
Jadhav, A.
Kornaga, E.
Laurinavicius, A.
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Lima, J.
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Pantanowitz, L.
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Wu, Y.
Yang, H.
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[10] The prognostic value of the P53 protein and the Ki67 marker in breast cancer patients
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