Arcyriaflavin a, a cyclin D1–cyclin-dependent kinase4 inhibitor, induces apoptosis and inhibits proliferation of human endometriotic stromal cells: a potential therapeutic agent in endometriosis

被引:0
作者
Tomoko Hirakawa
Kaei Nasu
Yoko Aoyagi
Kanetoshi Takebayashi
Hisashi Narahara
机构
[1] Oita University,Department of Obstetrics and Gynecology, Faculty of Medicine
[2] Oita University,Division of Obstetrics and Gynecology, Support System for Community Medicine, Faculty of Medicine
来源
Reproductive Biology and Endocrinology | / 15卷
关键词
Endometriosis; Cyclin D1 inhibitor; Cell cycle; Apoptosis; Cell proliferation;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 100 条
[1]  
Giudice LC(2004)Endometriosis Lancet 364 1789-1799
[2]  
Kao LC(2010)Mevalonate-Ras homology (rho)/rho-associated coiled-coil-forming protein kinase (ROCK)-mediated signaling pathway as a therapeutic target for the treatment of endometriosis-associated fibrosis Curr Signal Transduct Ther 5 141-148
[3]  
Nasu K(2011)Aberrant expression of apoptosis-related molecules in endometriosis: a possible mechanism underlying the pathogenesis of endometriosis Reprod Sci 18 206-218
[4]  
Yuge A(2015)Enhanced miR-210 expression promotes the pathogenesis of endometriosis through activation of signal transducer and activator of transcription 3 Hum Reprod 30 632-641
[5]  
Tsuno A(2016)miR-503, a microRNA epigenetically repressed in endometriosis, induces apoptosis and cell-cycle arrest and inhibits cell proliferation, angiogenesis, and contractility of human ovarian endometriotic stromal cells Hum Reprod 31 2587-2597
[6]  
Narahara H(2013)miR-196b targets c-myc and Bcl-2 expression, inhibits proliferation and induces apoptosis in endometriotic stromal cells Hum Reprod 28 750-761
[7]  
Nasu K(2003)Novel, potent and selective cyclin D1/CDK4 inhibitors: indolo[6,7-a] pyrrolo[3,4-c]carbazoles Bioorg Med Chem Lett 13 2261-2267
[8]  
Nishida M(2003)Aryl[a]pyrrolo[3,4-c]carbazoles as selective cyclin D1-CDK4 inhibitors Bioorg Med Chem Lett 13 3835-3839
[9]  
Kawano Y(1999)Indolocarbazoles: potent, selective inhibitors of human cytomegalovirus replication Bioorg Med Chem 6 1067-1074
[10]  
Tsuno A(2007)Two indolocarbazole alkaloids with apoptosis activity from a marine-derived actinomycete Z(2)039-2 Arch Pharm Res 30 270-274