Acute myeloid leukemia and transcription factors: role of erythroid Krüppel-like factor (EKLF)

被引：0
|
作者：
Rosa Ayala
Joaquin Martínez-López
Florinda Gilsanz
机构：
[1] Universidad Complutense de Madrid,Department of Medicine
[2] Hospital Universitario,Hematology Division
来源：
Cancer Cell International | / 12卷
关键词：
Acute myeloid leukemia; Transcription factors; EKLF; GATA1; GATA2; cMPL; FLT3; NPM1; CEBPA mutations;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We have investigated the role of erythroid transcription factors mRNA expression in patients with acute myeloid leukemia (AML) in the context of cytogenetic and other prognostic molecular markers, such as FMS-like Tyrosine Kinase 3 (FLT3), Nucleophosmin 1 (NPM1), and CCAAT/enhance-binding protein α (CEBPA) mutations. Further validation of Erythroid Krüppel-like Factor (EKLF) mRNA expression as a prognostic factor was assessed.
引用
收藏
相关论文
共 50 条
  • [1] Acute myeloid leukemia and transcription factors: role of erythroid Kruppel-like factor (EKLF)
    Ayala, Rosa
    Martinez-Lopez, Joaquin
    Gilsanz, Florinda
    CANCER CELL INTERNATIONAL, 2012, 12
  • [2] Erythroid Krüppel-like transcription factor (Eklf) maps to a region of mouse Chromosome 8 syntenic with human Chromosome 19
    Nancy A. Jenkins
    Debra J. Gilbert
    Neal G. Copeland
    Eugenia Gruzglin
    James J. Bieker
    Mammalian Genome, 1998, 9 : 174 - 176
  • [3] Krüppel-like transcription factors and control of pluripotency
    Pierre-Yves Bourillot
    Pierre Savatier
    BMC Biology, 8
  • [4] Sp1- and Krüppel-like transcription factors
    Joanna Kaczynski
    Tiffany Cook
    Raul Urrutia
    Genome Biology, 4
  • [5] Krüppel-like factors in cancer
    Marie-Pier Tetreault
    Yizeng Yang
    Jonathan P. Katz
    Nature Reviews Cancer, 2013, 13 : 701 - 713
  • [6] Role of Krüppel-like factors in pulmonary arterial hypertension
    Nicoleau, Salina
    Fellows, Adam
    Wojciak-Stothard, Beata
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2021, 134
  • [7] Role of Krüppel-like factors in cancer stem cells
    Yueling Zhang
    Jin Hao
    Yingcheng Zheng
    Dian Jing
    Yu Shen
    Jun Wang
    Zhihe Zhao
    Journal of Physiology and Biochemistry, 2015, 71 : 155 - 164
  • [8] Myeloid Krüppel-like factor 2 is a critical regulator of metabolic inflammation
    David R. Sweet
    Neelakantan T. Vasudevan
    Liyan Fan
    Chloe E. Booth
    Komal S. Keerthy
    Xudong Liao
    Vinesh Vinayachandran
    Yoichi Takami
    Derin Tugal
    Nikunj Sharma
    E. Ricky Chan
    Lilei Zhang
    Yulan Qing
    Stanton L. Gerson
    Chen Fu
    Anthony Wynshaw-Boris
    Panjamaporn Sangwung
    Lalitha Nayak
    Paul Holvoet
    Keiichiro Matoba
    Yuan Lu
    Guangjin Zhou
    Mukesh K. Jain
    Nature Communications, 11
  • [9] Direct competition between DNA binding factors highlights the role of Krüppel-like Factor 1 in the erythroid/megakaryocyte switch
    Laura J. Norton
    Samantha Hallal
    Elizabeth S. Stout
    Alister P. W. Funnell
    Richard C. M. Pearson
    Merlin Crossley
    Kate G. R. Quinlan
    Scientific Reports, 7
  • [10] Elevated Krüppel-like factor 4 transcription factor in canine mammary carcinoma
    Pei-Yi Chu
    Nicholas Chung-Heng Hsu
    Albert Taiching Liao
    Kun-Tu Yeh
    Ming-Feng Hou
    Chen-Hsuan Liu
    BMC Veterinary Research, 7
12345