Electrochemical behavior of the N-nosyl-protected amino acids in N,N-dimethylformamide

The electrochemical reduction of serine, glycine, and leucine protected by the 4-nitrobenzenesulfonyl group in N,N-dimethylformamide at mercury cathode occurs at two steps. The first one at −0.8 V vs. SCE, after a one-electron transfer, leads the anion radical formation that dimerizes and adsorbs at electrode. In the second step at −1.4 V, an instable dianion forms which then cleaves. The mechanism is discussed.