Rational use of Jatropha curcas L. in food and medicine: from toxicity problems to safe applications

被引:0
作者
Muhamad Insanu
Chryssa Dimaki
Richard Wilkins
John Brooker
Piet van der Linde
Oliver Kayser
机构
[1] University of Groningen,Department of Pharmaceutical Biology
[2] Institut Teknologi Bandung,School of Pharmacy
[3] University of Newcastle,School of Agriculture Food and Rural Development
[4] Quinvita NV,Technical Biochemistry
[5] Technical University Dortmund,undefined
来源
Phytochemistry Reviews | 2013年 / 12卷
关键词
Biorefinery; Detoxification; Secondary natural products; Anticancer; Toxicity; Phorbol esters; Cyclic peptides; Biochemical engineering;
D O I
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中图分类号
学科分类号
摘要
Jatropha curcas L. has become an important plant for biorefinery and production of biodiesel. From its ethnobotanical use, the plant is known for several activities which are associated with high toxicity. The latest development in engineering technology enables detoxification of native oil and other parts of the plant for new pharmaceutical purposes. Hence a revised look to the rich metabolic spectra of partly structurally rare secondary compound becomes an interesting field of research to be explored. In this review, we discuss recent developments in the technology of detoxification process and give insight about how this ethnomedicinal plant can be applied to new fields of experimental medicine. The review highlights recent data on biological activities and discusses concepts and strategies for turning a poison plant into a valuable crop with high pharmaceutical potential.
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页码:107 / 119
页数:12
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