Tailored Therapeutic Doses of Dexmedetomidine in Evolving Neuroinflammation after Traumatic Brain Injury

被引:0
作者
Dicle Karakaya
Canan Cakir-Aktas
Sennur Uzun
Figen Soylemezoglu
Melike Mut
机构
[1] Hacettepe University,Faculty of Medicine, Department of Neurosurgery
[2] Hacettepe University,Institute of Neurological Sciences and Psychiatry
[3] Hacettepe University,Faculty of Medicine, Department of Anesthesiology and Reanimation
[4] Hacettepe University,Faculty of Medicine, Department of Pathology
来源
Neurocritical Care | 2022年 / 36卷
关键词
Traumatic brain injury; Neuroinflammation; Inflammasome; NLRP3; Microglia; T cells; Dexmedetomidine;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:802 / 814
页数:12
相关论文
共 331 条
  • [1] Maas AI(2008)Moderate and severe traumatic brain injury in adults Lancet Neurol 7 728-741
  • [2] Stocchetti N(2013)The epidemiology of traumatic brain injury The Lancet Neurology 12 28-29
  • [3] Bullock R(2015)The neuropathology of traumatic brain injury Handb Clin Neurol 127 45-66
  • [4] Andelic N(2016)Neuroinflammation in animal models of traumatic brain injury J Neurosci Methods 272 38-49
  • [5] McKee AC(2000)Traumatic brain injury The Lancet 356 923-929
  • [6] Daneshvar DH(2007)Pathophysiology of traumatic brain injury BJA Br J Anaesth 99 4-9
  • [7] Chiu CC(2000)Recent advances in neurotrauma J Neuropathol Exp Neurol 59 641-651
  • [8] Liao YE(2017)NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies Front Cell Neurosci 11 63-35
  • [9] Yang LY(1991)Head trauma as a risk factor for Alzheimer’s disease: a collaborative re-analysis of case-control studies. EURODEM Risk Factors Research Group Int J Epidemiol 20 S28-6569
  • [10] Wang JY(2015)Closed head injury in an age-related Alzheimer mouse model leads to an altered neuroinflammatory response and persistent cognitive impairment J Neurosci 35 6554-22