Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia

被引：0

作者：

Zhiqiang Li

Jianhua Chen

Hao Yu

Lin He

Yifeng Xu

Dai Zhang

Qizhong Yi

Changgui Li

Xingwang Li

Jiawei Shen

Zhijian Song

Weidong Ji

Meng Wang

Juan Zhou

Boyu Chen

Yahui Liu

Jiqiang Wang

Peng Wang

Ping Yang

Qingzhong Wang

Guoyin Feng

Benxiu Liu

Wensheng Sun

Baojie Li

Guang He

Weidong Li

Chunling Wan

Qi Xu

Wenjin Li

Zujia Wen

Ke Liu

Fang Huang

Jue Ji

Stephan Ripke

Weihua Yue

Patrick F Sullivan

Michael C O'Donovan

Yongyong Shi

机构：

[1] Affiliated Hospital of Qingdao University and Biomedical Sciences Institute of Qingdao University (Qingdao Branch of SJTU Bio-X Institutes),Department of Psychiatry

[2] Qingdao University,Department of Psychiatry

[3] Bio-X Institutes,Department of Psychiatry and Psychotherapy

[4] Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education),Departments of Genetics and Psychiatry

[5] Collaborative Innovation Center for Brain Science,Department of Medical Epidemiology and Biostatistics

[6] Shanghai Jiao Tong University,Division of Psychological Medicine and Clinical Neurosciences

[7] Institute of Social Cognitive and Behavioral Sciences,undefined

[8] Shanghai Jiao Tong University,undefined

[9] Institute of Neuropsychiatric Science and Systems Biological Medicine,undefined

[10] Shanghai Jiao Tong University,undefined

[11] Shanghai Key Laboratory of Psychotic Disorders,undefined

[12] Shanghai Mental Health Center,undefined

[13] Shanghai Jiao Tong University School of Medicine,undefined

[14] Tsinghua-Peking Joint Center for Life Sciences,undefined

[15] School of Life Sciences,undefined

[16] Tsinghua University,undefined

[17] Institute of Mental Health,undefined

[18] Sixth Hospital,undefined

[19] Peking University,undefined

[20] Jining Medical University,undefined

[21] Peking-Tsinghua Joint Center for Life Sciences/PKU-IDG/McGovern Institute for Brain Research,undefined

[22] Peking University,undefined

[23] First Teaching Hospital of Xinjiang Medical University,undefined

[24] Shandong Provincial Key Laboratory of Metabolic Disease and Metabolic Disease Institute of Qingdao University,undefined

[25] Changning Mental Health Center,undefined

[26] Wuhu Fourth People's Hospital,undefined

[27] Longquan Mountain Hospital of Guangxi Province,undefined

[28] National Laboratory of Medical Molecular Biology,undefined

[29] Institute of Basic Medical Sciences,undefined

[30] Chinese Academy of Medical Sciences and Peking Union Medical College,undefined

[31] Analytic and Translational Genetics Unit,undefined

[32] Massachusetts General Hospital,undefined

[33] Stanley Center for Psychiatric Research,undefined

[34] Broad Institute of MIT and Harvard,undefined

[35] Charité-Universitätsmedizin,undefined

[36] University of North Carolina,undefined

[37] Karolinska Institutet,undefined

[38] MRC Centre for Neuropsychiatric Genetics and Genomics,undefined

[39] School of Medicine,undefined

[40] Cardiff University,undefined

来源：

Nature Genetics | 2017年 / 49卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

A genome-wide association analysis using data from Chinese individuals combined with a transethnic meta-analysis of Psychiatry Genomics Consortium data identifies 30 new loci for schizophrenia. These analyses improve the fine-mapping of susceptibility loci and implicate multiple pathways in schizophrenia biology.

引用

页码：1576 / 1583

页数：7

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