A novel PDPN antagonist peptide CY12-RP2 inhibits melanoma growth via Wnt/β-catenin and modulates the immune cells

被引：0
作者：
Chunyan Feng
Albert Yu
Zhongfu Wang
Kun Wang
Jiawei Chen
Yaojiong Wu
Ting Deng
Huaqing Chen
Yibo Hou
Shaohua Ma
Xiaoyong Dai
Laiqiang Huang
机构：
[1] Tsinghua University,Institute of Biopharmaceutical and Health Engineering, Shenzhen Key Laboratory of Gene and Antibody Therapy, State Key Laboratory of Chemical Oncogenomics, Shenzhen International Graduate School
[2] Tsinghua University,School of Life Sciences
[3] Shenzhen People’s Hospital,Department of Interventional Radiology
来源：
Journal of Experimental & Clinical Cancer Research | / 43卷
关键词：
Melanoma; PDPN; CY12-RP2 peptide; EMT; Wnt/β-catenin pathway; Immune activation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 327 条
  • [1] Gupta AK(2016)Skin cancer concerns in people of color: risk factors and prevention Asian Pac J Cancer Prev 17 5257-5264
  • [2] Bharadwaj M(2020)Spontaneously occurring melanoma in animals and their relevance to human melanoma J Pathol 252 4-21
  • [3] Mehrotra R(2018)Melanoma treatment in review Immunotargets Ther 7 35-49
  • [4] van der Weyden L(2020)Melanoma Risk and Melanocyte Biology Acta Derm Venereol 100 adv00139-68
  • [5] Brenn T(2017)Surgical resection of metastatic melanoma in the era of immunotherapy and targeted therapy Melanoma Manag 4 61-351
  • [6] Patton EE(2020)Managing metastatic melanoma in 2022: a clinical review JCO Oncol Pract 18 335-810
  • [7] Wood GA(2020)Clinical development of BRAF plus MEK Inhibitor Combinations Trends Cancer 6 797-1299
  • [8] Adams DJ(2019)Podoplanin (PDPN) affects the invasiveness of thyroid carcinoma cells by inducing ezrin, radixin and moesin (E/R/M) phosphorylation in association with matrix metalloproteinases BMC Cancer 19 85-164
  • [9] Domingues B(2018)Podoplanin: an emerging cancer biomarker and therapeutic target Cancer Sci 109 1292-4399
  • [10] Lopes JM(2022)Roles of Podoplanin in Malignant Progression of Tumor Cells 11 575-229
12345678910