Synthesis of 1-substituted (R,S)-8-(2-methoxy-5-methylphenyl)-3,3,9-trimethyl-2-azaspiro[4.5]deca-1,7-dien-6-ones

被引:0
|
作者
Yu. V. Shklyaev
Yu. V. Nifontov
A. S. Shashkov
S. I. Firgang
机构
[1] Institute of Technical Chemistry,Ural Branch of the Russian Academy of Sciences
[2] N. D. Zelinsky Institute of Organic Chemistry,Russian Academy of Sciences
来源
Russian Chemical Bulletin | 2002年 / 51卷
关键词
nitrogen-containing spiroheterocycles; -methylanisole; isobutyraldehyde; nitriles; Ritter reaction; -spiroheterocyclization; alkylation;
D O I
暂无
中图分类号
学科分类号
摘要
Reactions between p-methylanisole, isobutyraldehyde, and nitriles (acetonitrile, methyl thiocyanate, or ethyl cyanoacetate) in conc. H2SO4 yield 1-substituted (R,S)-8-(2-methoxy-5-methylphenyl)-3,3,9-trimethyl-2-azaspiro[4.5]deca-1,7-dien-6-ones.
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页码:2234 / 2237
页数:3
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