Cooperation of adenosine and prostaglandin E2 (PGE2) in amplification of cAMP–PKA signaling and immunosuppression

[1] Hata AN(2004)Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation Pharmacol Ther 103 147-166

[2] Breyer RM(2005)Differential regulation of phosphorylation of the cAMP response element-binding protein after activation of EP2 and EP4 prostanoid receptors by prostaglandin E2 Mol Pharmacol 68 251-259

[3] Fujino H(2003)Targeting cyclooxygenase-2 in human neoplasia: rationale and promise Cancer Cell 4 431-436

[4] Salvi S(2004)Prognostic impact of cyclooxygenase-2 in breast cancer Clin Breast Cancer 4 428-433

[5] Regan JW(2005)Cyclooxygenase-2 is an independent prognostic factor in gastric cancer and its expression is regulated by the messenger RNA stability factor HuR Clin Cancer Res 11 7362-7368

[6] Dannenberg AJ(1990)Indomethacin up-regulates the generation of lymphokine-activated killer-cell activity and antibody-dependent cellular cytotoxicity mediated by interleukin-2 Cancer Immunol Immunother 31 342-348

[7] Subbaramaiah K(2002)Selective cyclooxygenase (COX)-1 or COX-2 inhibitors control metastatic disease in a murine model of breast cancer Cancer Res 62 2343-2346

[8] Denkert C(2005)Cyclooxygenase inhibitors modulate NK activities that control metastatic disease Cancer Immunol Immunother 54 981-987

[9] Winzer KJ(1988)Cure of B16F10 melanoma lung metastasis in mice by chronic indomethacin therapy combined with repeated rounds of interleukin 2: characteristics of killer cells generated in situ Cancer Res 48 1072-1079

[10] Hauptmann S(2000)Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice Cancer Res 60 4705-4708

[1] Hata AN(2004)Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation Pharmacol Ther 103 147-166

[2] Breyer RM(2005)Differential regulation of phosphorylation of the cAMP response element-binding protein after activation of EP2 and EP4 prostanoid receptors by prostaglandin E2 Mol Pharmacol 68 251-259

[3] Fujino H(2003)Targeting cyclooxygenase-2 in human neoplasia: rationale and promise Cancer Cell 4 431-436

[4] Salvi S(2004)Prognostic impact of cyclooxygenase-2 in breast cancer Clin Breast Cancer 4 428-433

[5] Regan JW(2005)Cyclooxygenase-2 is an independent prognostic factor in gastric cancer and its expression is regulated by the messenger RNA stability factor HuR Clin Cancer Res 11 7362-7368

[6] Dannenberg AJ(1990)Indomethacin up-regulates the generation of lymphokine-activated killer-cell activity and antibody-dependent cellular cytotoxicity mediated by interleukin-2 Cancer Immunol Immunother 31 342-348

[7] Subbaramaiah K(2002)Selective cyclooxygenase (COX)-1 or COX-2 inhibitors control metastatic disease in a murine model of breast cancer Cancer Res 62 2343-2346

[8] Denkert C(2005)Cyclooxygenase inhibitors modulate NK activities that control metastatic disease Cancer Immunol Immunother 54 981-987

[9] Winzer KJ(1988)Cure of B16F10 melanoma lung metastasis in mice by chronic indomethacin therapy combined with repeated rounds of interleukin 2: characteristics of killer cells generated in situ Cancer Res 48 1072-1079

[10] Hauptmann S(2000)Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice Cancer Res 60 4705-4708