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Resistant Microascus cirrosus pneumonia can be treated with a combination of surgery, multiple anti-fungal agents and a growth factor
被引:0
|作者:
Celalettin Ustun
Gerwin Huls
Marc Stewart
Kieren A. Marr
机构:
[1] Medical College of Georgia,The Department of Internal Medicine, Section of Hematology/Oncology
[2] University Medical Center Groningen,Department of Hematology
[3] Fred Hutchinson Cancer Research Center,Department of Medicine, Section of Hematology/Oncology
[4] Program in Infectious Diseases,undefined
[5] Fred Hutchinson Cancer Research Center,undefined
来源:
Mycopathologia
|
2006年
/
162卷
关键词:
bone marrow transplantation;
fungal infection;
s;
pneumonia;
D O I:
暂无
中图分类号:
学科分类号:
摘要:
A 49-year old male with acute myelogenous leukemia relapsed eight years post allogeneic bone marrow transplantation. The patient received induction chemotherapy causing prolonged neutropenia. The patient developed pneumonia for which empirical antibacterial and antifungal therapy were started. The patient underwent a video-assisted thorocascopy with near complete resection of the lesion because of poor response to treatment. Microascus cirrosus was identified in the tissue. In vitro susceptibility test to different antifungal agents showed M. cirrosus was very resistant. The patient is undergoing second allogeneic transplant with improved pneumonia resulting from a combination of treatment for fungal infection, which included surgery, antifungal agents, and granulocyte-colony stimulating factor. The Microascus genus rarely causes invasive fungal infection in humans and can be very difficult to treat because of the resistance to available antifungal agents.
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页码:299 / 302
页数:3
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