Detection of a Novel Truncated WT1 Transcript in Human Neoplasia

被引：0
|
作者：
Chavaboon Dechsukhum
Joy L. Ware
Andrea Ferreira-Gonzalez
David S. Wilkinson
Carleton T. Garrett
机构：
[1] Medical College of Virginia Campus of Virginia Commonwealth University,Department of Pathology
来源：
Molecular Diagnosis | 2000年 / 5卷 / 2期
关键词：
WT1; prostate cancer; novel transcript;
D O I：
10.1007/BF03262030
中图分类号：
学科分类号：
摘要：
Background: The Wilms’ tumor 1 (WT1) gene encodes a transcription factor critical in urogenital development. Using a new model of prostate cancer progression that permits comparison of the cellular and molecular properties of increasingly aggressive sublines of simian virus 40 large T-antigen—immortalized human prostate epithelial cells within the same lineage, the role of WT1 in tumorigenesis was investigated.
引用
收藏
页码：117 / 128
页数：11
相关论文
共 50 条
  • [21] WT1 and kidney progenitor cells
    Kreidberg, Jordan A.
    ORGANOGENESIS, 2010, 6 (02) : 61 - 70
  • [22] Wt1 and Epicardial Fate Mapping
    Rudat, Carsten
    Kispert, Andreas
    CIRCULATION RESEARCH, 2012, 111 (02) : 165 - U97
  • [23] The role of WT1 gene in neuroblastoma
    Wang, Jingfu
    Oue, Takaharu
    Uehara, Shuichiro
    Yamanaka, Hiroaki
    Oji, Yusuke
    Fukuzawa, Masahiro
    JOURNAL OF PEDIATRIC SURGERY, 2011, 46 (02) : 326 - 331
  • [24] Wt1 is not essential for hematopoiesis in the mouse
    King-Underwood, L
    Little, S
    Baker, M
    Clutterbuck, R
    Delassus, S
    Enver, T
    Lebozer, C
    Min, T
    Moore, A
    Schedl, A
    Pritchard-Jones, K
    LEUKEMIA RESEARCH, 2005, 29 (07) : 803 - 812
  • [25] Editorial: WT1 in Development and Disease
    Chau, You-Ying
    Martinez-Estrada, Ofelia M.
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 10
  • [26] Midkine as a novel target gene for the Wilms' tumor suppressor gene (WT1)
    Adachi, Y
    Matsubara, S
    Pedraza, C
    Ozawa, M
    Tsutsui, J
    Takamatsu, H
    Noguchi, H
    Akiyama, T
    Muramatsu, T
    ONCOGENE, 1996, 13 (10) : 2197 - 2203
  • [27] Immunohistochemical detection of the Wilms' tumor gene (WT1) in epithelial ovarian tumors
    Shimizu, M
    Toki, T
    Takagi, Y
    Konishi, I
    Fujii, S
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 2000, 19 (02) : 158 - 163
  • [28] WT1 Trio Peptide-Based Cancer Vaccine for Rare Cancers Expressing Shared Target WT1
    Oji, Yusuke
    Kagawa, Naoki
    Arita, Hideyuki
    Naka, Norifumi
    Hamada, Ken-ichiro
    Outani, Hidetatsu
    Shintani, Yasushi
    Takeda, Yoshito
    Morii, Eiichi
    Shimazu, Kenzo
    Suzuki, Motoyuki
    Nishida, Sumiyuki
    Nakata, Jun
    Tsuboi, Akihiro
    Iwai, Miki
    Hayashi, Sae
    Imanishi, Rin
    Ikejima, Sayaka
    Kanegae, Mizuki
    Iwamoto, Masahiro
    Ikeda, Mayu
    Yagi, Kento
    Shimokado, Haruka
    Nakajima, Hiroko
    Hasegawa, Kana
    Morimoto, Soyoko
    Fujiki, Fumihiro
    Nagahara, Akira
    Tanemura, Atsushi
    Ueda, Yutaka
    Mizushima, Tsunekazu
    Ohmi, Masato
    Ishida, Takayuki
    Fujimoto, Manabu
    Nonomura, Norio
    Kimura, Tadashi
    Inohara, Hidenori
    Okada, Seiji
    Kishima, Haruhiko
    Hosen, Naoki
    Kumanogoh, Atsushi
    Oka, Yoshihiro
    Sugiyama, Haruo
    CANCERS, 2023, 15 (02)
  • [29] WT1 in acute leukemia, chronic myelogenous leukemia and myelodysplastic syndrome: therapeutic potential of WT1 targeted therapies
    Rosenfeld, C
    Cheever, MA
    Gaiger, A
    LEUKEMIA, 2003, 17 (07) : 1301 - 1312
  • [30] WT1 CpG islands methylation in human lung cancer: A pilot study
    Bruno, Pierdonato
    Gentile, Giovanna
    Mancini, Rita
    De Vitis, Claudia
    Esposito, Maria Cristina
    Scozzi, Davide
    Mastrangelo, Mario
    Ricci, Alberto
    Mohsen, Ibrahim
    Ciliberto, Gennaro
    Simmaco, Maurizio
    Mariotta, Salvatore
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2012, 426 (03) : 306 - 309
12345