Short review: Metabolism of theFusarium mycotoxins deoxynivalenol and zearalenone in plants

被引：27
作者：
F. Berthiller
M. Lemmens
U. Werner
R. Krska
M. T. Hauser
G. Adam
R. Schuhmacher
机构：
[1] University of Natural Resources and Applied Life Sciences,Christian Doppler Laboratory for Mycotoxin Research, Department of Agrobiotechnology (IFA
[2] University of Natural Resources and Applied Life Sciences,Tulln)
[3] University of Natural Resources and Applied Life Sciences,Institute for Biotechnology in Plant Production, Department of Agrobiotechnology (IFA
来源：
Mycotoxin Research | 2007年 / 23卷 / 2期
关键词：
deoxynivalenol; zearalenone; conjugated mycotoxins; masked mycotoxins; metabolism; mass spectrometry;
D O I：
10.1007/BF02946028
中图分类号：
学科分类号：
摘要：
Plants have a high capacity to transform and thereby detoxify deleterious or poisonous compounds, like mycotoxins. The formation of glucose conjugates has a central role in this process. Mammals, however, are able to (partly) release the precursor substances during digestion, reactivating the mycotoxins. This short review provides a brief summary about the metabolism of theFusarium mycotoxins deoxynivalenol and zearalenone in plants. Two examples are discussed in greater detail. First, the formation of deoxynivalenol-3-glucoside in wheat is linked to a quantitative trait locus that is often used forFusarium head blight resistance breeding. Secondly, the metabolism of zearalenone inArabidopsis thaliana results in at least 17 different metabolites, all of which are potentially hazardous for humans and animals.
引用
收藏
页码：68 / 72
页数：4
相关论文
共 82 条
[1]  
Kreuz K(1996)Old Enzymes for a New Job: Herbicide Detoxification in Plants Plant Physiol 111 349-353
[2]  
Tommasini R(1990)Cleavage of zearalenoneglycoside, a “masked” mycotoxin, during digestion in swine J Vet Med 37 236-240
[3]  
Martinoia E(1983)Fusarium toxins in field corn. I. Time course of fungal growth and production of deoxynivalenol and other mycotoxins Can J Bot 61 3080-3087
[4]  
Gareis M(1984)Effect of milling and baking on deoxynivalenol (vomitoxin) content of eastern Canadian wheats J Agric Food Chem 32 659-664
[5]  
Bauer J(1991)Deoxynivalenol fatty acid and glucoside conjugates J Agric Food Chem 39 570-574
[6]  
Thiem J(1992)Structure elucidation of a plant metabolite of 4-desoxynivalenol Tetrahedron 3 953-960
[7]  
Plank G(2003)Detoxification of the J Biol Chem 278 47905-47914
[8]  
Grabley S(2005) Mycotoxin Deoxynivalenol by a UDP-glucosyltransferase from J Agric Food Chem 53 3421-3425
[9]  
Gedek B(1988)Masked Mycotoxins: Determination of a Deoxynivalenol Glucoside in Artificially and Naturally Contaminated Wheat by LC-MS/MS Naturwissenschaften 75 309-310
[10]  
Miller JD(2002)Transformation of the J Agric Food Chem 50 1736-1738
123456789