Correlation of RET somatic mutations with clinicopathological features in sporadic medullary thyroid carcinomas

被引：0
作者：
M M Moura
B M Cavaco
A E Pinto
R Domingues
J R Santos
M O Cid
M J Bugalho
V Leite
机构：
[1] Centro de Investigação de Patobiologia Molecular (CIPM),
[2] Instituto Português de Oncologia de Lisboa Francisco Gentil E.P.E.,undefined
[3] Rua Prof. Lima Basto,undefined
[4] Serviço de Anatomia Patológica,undefined
[5] Instituto Português de Oncologia de Lisboa Francisco Gentil E.P.E.,undefined
[6] Rua Prof. Lima Basto,undefined
[7] Serviço de Cirurgia Cabeça e Pescoço,undefined
[8] Instituto Português de Oncologia de Lisboa Francisco Gentil E.P.E.,undefined
[9] Rua Prof. Lima Basto,undefined
[10] Serviço de Endocrinologia,undefined
[11] Instituto Português de Oncologia de Lisboa Francisco Gentil E.P.E.,undefined
[12] Rua Prof. Lima Basto,undefined
[13] Faculdade de Ciências Médicas,undefined
[14] Universidade Nova de Lisboa,undefined
[15] Campo Mártires da Pátria 130,undefined
来源：
British Journal of Cancer | 2009年 / 100卷
关键词：
sporadic medullary thyroid carcinoma; proto-oncogene; somatic mutation; genetic screening; prognosis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Screening of REarranged during Transfection (RET) gene mutations has been carried out in different series of sporadic medullary thyroid carcinomas (MTC). RET-positive tumours seem to be associated to a worse clinical outcome. However, the correlation between the type of RET mutation and the patients' clinicopathological data has not been evaluated yet.
引用
收藏
页码：1777 / 1783
页数：6
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