The influence of corneal hysteresis and corneal resistance factor on the measurement of intraocular pressure

被引:24
作者
Hager A. [1 ,3 ]
Schroeder B. [1 ]
Sadeghi M. [1 ]
Großherr M. [2 ]
Wiegand W. [1 ]
机构
[1] Augenabteilung, Asklepios Klinik Nord - Heidberg, Hamburg
[2] Klinik für Anästhesiologie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck
[3] Augenabteilung, Asklepios Klinik Nord - Heidberg, 22415 Hamburg
来源
Der Ophthalmologe | 2007年 / 104卷 / 6期
关键词
Corneal hysteresis; Goldmann applanation tonometry; Non-contact tonometry; Viscoelastic properties of the cornea;
D O I
10.1007/s00347-007-1532-y
中图分类号
学科分类号
摘要
The influence of central corneal thickness (CCT) on the measurement of intraocular pressure (IOP) has been discussed extensively in recent years. The problem, however, has not been solved so far. In addition to CCT there are probably further biomechanical properties that play a role in IOP measurement. We wanted to find out whether these properties are related to Goldmann applanation tonometry (GAT), noncontact tonometry (NCT), or CCT. Biomechanical properties of the cornea such as corneal hysteresis (CH) and corneal resistance factor (CRF) can be measured with the Ocular Response Analyzer (ORA, Reichert Ophthalmic Instruments, Depew, NY, USA). Furthermore, a corneal compensated IOP (IOPcc) is given. We examined 156 normal eyes of 80 patients who did not show corneal pathology nor glaucoma. In each eye GAT, NCT, and ORA data as well as CCT were measured. Data were statistically analyzed with respect to agreement and the influence of CH and CRF on IOP measurement. In our patients the following average values were calculated: GAT 14.8±3.0 mmHg, NCT 16.4±3.9 mmHg, IOPcc 16.2±4.1 mmHg, CH 10.6±2.3 mmHg, CRF 10.9±2.4 mmHg, and CCT 557±36 μm. IOPcc was not related to CCT in normal eyes and the only IOP value related to CH (p<0.01). CRF, however, was related to GAT and NCT values (p<0.01). In our group of normal eyes IOPcc, i.e., the value that is adjusted by measurement of viscoelastic properties of the cornea, in contrast to GAT and NCT does not depend on central corneal thickness. Corneal hysteresis and corneal resistance factor provide further information about biomechanical properties of the cornea beyond central corneal thickness. © Springer Medizin Verlag 2007.
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页码:484 / 489
页数:5
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  • [1] Bland J.M., Altmann D.G., Measuring agreement in method comparison studies, Stat Methods Med Res, 8, pp. 135-160, (1999)
  • [2] Congdon N.G., Broman A.T., Bandeen-Roche K., Et al., Central corneal thickness and corneal hysteresis associated with glaucoma damage, Am J Ophthalmol, 141, pp. 868-875, (2006)
  • [3] Domke N., Hager A., Wiegand W., Augeninnendruck und Hornhautdicke. Ein Vergleich zwischen Non-Contact-Tonometrie und Applanationstonornetrie, Ophthalnnologe, 103, pp. 583-587, (2006)
  • [4] Draeger J., Jessen K., Haselmann G., Klinische und experimentelle Untersuchungen mit dem Non-contact-Tonometer, Klin Monatsbl Augenheilkd, 167, pp. 27-34, (1975)
  • [5] Hager A., Dave H., Wiegand W., Hornhautpachymetrie und Augeninnendruck, Klin Monatsbl Augenheilkd, 222, pp. 558-567, (2005)
  • [6] Herndon L.W., Measuring intraocular pressure-adjustments for corneal thickness and new technologies, Curr Opin Ophthalmol, 17, pp. 115-119, (2006)
  • [7] Laiquzzaman M., Bhojwani R., Cunliffe I., Shah S., Diurnal variation of ocular hysteresis in normal subjects: Relevance in clinical context, Clin Experiment Ophthalmol, 34, pp. 114-118, (2006)
  • [8] Luce D.A., Determining in vivo biomechanical properties of the cornea with an ocular response analyzer, J Cataract Refract Surg, 31, pp. 156-162, (2005)
  • [9] Medeiros F.A., Weinreb R.N., Evaluation of the influence of corneal biomechanical properties on intraocular pressure measurements using the Ocular Response Analyzer, J Glaucoma, 15, pp. 364-370, (2006)
  • [10] Tonnu P.A., Ho T., Newson T., Et al., The influence of central corneal thickness and age in intraocular pressure measured by pneumotonometry, non-contact-tonometry, the Tono-Pen XL, and Goldmann applanation tonometry, Br J Ophthalmol, 89, pp. 851-854, (2005)