Transcriptomic perspectives of memory-like NK cells and aging

被引：0
作者：
Dandan Wang
Subramaniam Malarkannan
机构：
[1] Blood Research Institute,Department of Microbiology and Immunology
[2] Versiti Inc,Division of Hematology and Oncology, Department of Medicine
[3] Medical College of Wisconsin (MCW),Division of Hematology, Oncology, and Bone Marrow Transplantation, Department of Pediatrics
[4] MCW,undefined
[5] MCW,undefined
来源：
Genome Medicine | / 14卷
关键词：
Memory-like NK cells, Aging, Inflammaging, HCMV, COVID-19;
D O I：
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摘要：
A recent study highlights the presence of a unique memory-like natural killer (NK) cell subset, which accumulates with aging and appears to associate withdisease severity in COVID-19 patients. While the clinical relevance of memory in NK cells is being debated, the molecular identity of this subset in the form of a single-cell transcriptome is essential to define their origin, longevity, functions, and disease relevance.
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