Advancement of human leukocyte antigen-partially matched related hematopoietic stem cell transplantation

被引：0
|
作者：
Xiaodong Mo
Xiaojun Huang
机构：
[1] Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation,Peking University People’s Hospital & Institute of Hematology
来源：
Frontiers of Medicine | 2013年 / 7卷
关键词：
partially matched related donor; hematopoietic stem cell transplantation; allogeneic;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Allogeneic hematopoietic stem cell transplantation (HSCT) is one of the most effective options for hematological malignancies, and human leukocyte antigen-partially matched related donors (PMRDs) are a valuable option for HSCT. Several protocols (with or without ex vivo T-cell depletion (TCD)) have been established worldwide. TCD including CD34+ positive selection and CD3/CD19 depletion has successfully overcome the human leukocyte antigen disparity. However, TCD is associated with prolonged immune deficiencies, increased risks of infectious complications, and high transplantation-related mortality. PMRD HSCTwithout ex vivo TCD is well developed, and numerous patients have benefitted from it. Here, we review the literature on PMRD HSCT.
引用
收藏
页码：306 / 315
页数：9
相关论文
共 50 条
  • [1] Advancement of human leukocyte antigen-partially matched related hematopoietic stem cell transplantation
    Mo, Xiaodong
    Huang, Xiaojun
    FRONTIERS OF MEDICINE, 2013, 7 (03) : 306 - 315
  • [2] Nonmalignant Late Effects in Survivors of Partially Matched Donor Hematopoietic Stem Cell Transplantation
    Mo, Xiao-Dong
    Xu, Lan-Ping
    Liu, Dai-Hong
    Zhang, Xiao-Hui
    Chen, Huan
    Chen, Yu-Hong
    Han, Wei
    Wang, Yu
    Wang, Feng-Rong
    Wang, Jing-Zhi
    Liu, Kai-Yan
    Huang, Xiao-Jun
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2013, 19 (05) : 777 - 783
  • [3] RANTES Polymorphisms and the Risk of Graft-versus-Host Disease in Human Leukocyte Antigen-Matched Sibling Allogeneic Hematopoietic Stem Cell Transplantation
    Shin, Dong-Yeop
    Kim, Inho
    Kim, Jin Hee
    Lee, Yun-Gyoo
    Kang, Eun Joo
    Cho, Hyeon Jin
    Lee, Kyung-Hun
    Kim, Hye Jin
    Park, Eun-Hee
    Lee, Jong-Eun
    Bae, Ji-Yeon
    See, Cha Ja
    Yoon, Sung-Soo
    Park, Sung Sup
    Han, Kyou-Sup
    Park, Myoung Hee
    Hong, Yun-Chul
    Park, Seonyang
    Kim, Byoung Kook
    ACTA HAEMATOLOGICA, 2013, 129 (03) : 137 - 145
  • [4] Clonal Evolution Including Partial Loss of Human Leukocyte Antigen Genes Favoring Extramedullary Acute Myeloid Leukemia Relapse After Matched Related Allogeneic Hematopoietic Stem Cell Transplantation
    Stoelzel, Friedrich
    Hackmann, Karl
    Kuithan, Friederike
    Mohr, Brigitte
    Fuessel, Monika
    Oelschlaegel, Uta
    Thiede, Christian
    Roellig, Christoph
    Platzbecker, Uwe
    Schetelig, Johannes
    Illmer, Thomas
    Schaich, Markus
    Seliger, Barbara
    Hartmann, Arndt
    Baretton, Gustavo
    Zietz, Christian
    Ehninger, Gerhard
    Schrock, Evelin
    Bornhaeuser, Martin
    TRANSPLANTATION, 2012, 93 (07) : 744 - 749
  • [5] Partially Matched Related Hematopoietic Stem Cell Transplantation without Ex Vivo T Cell Depletion Compared with Matched Unrelated Transplantation in Adult Patients with Hematologic Malignancies
    Wang, Ying
    Chen, Feng
    Han, Yue
    Fu, Zheng-Zheng
    Tang, Xiao-Wen
    Miao, Miao
    Qiu, Hui-Ying
    Jin, Zheng-Ming
    Sun, Ai-Ning
    Wu, De-Pei
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2009, 15 (10) : 1258 - 1264
  • [6] Haploidentical T Cell-Replete Transplantation with Post-Transplantation Cyclophosphamide for Patients in or above the Sixth Decade of Age Compared with Allogeneic Hematopoietic Stem Cell Transplantation from an Human Leukocyte Antigen-Matched Related or Unrelated Donor
    Blaise, Didier
    Fuerst, Sabine
    Crocchiolo, Roberto
    El-Cheikh, Jean
    Granata, Angela
    Harbi, Samia
    Bouabdallah, Reda
    Devillier, Raynier
    Bramanti, Stephania
    Lemarie, Claude
    Picard, Christophe
    Chabannon, Christian
    Weiller, Pierre-Jean
    Faucher, Catherine
    Mohty, Bilal
    Vey, Norbert
    Castagna, Luca
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2016, 22 (01) : 119 - 124
  • [7] Comparative Study of the Efficacy of Allogeneic Hematopoietic Stem Cell Transplantation from Human Leukocyte Antigen-Haploidentical Related and Unrelated Donors in the Treatment of Leukemia
    Yang, Kai
    Si, Yingjian
    Chen, Huiren
    He, Xuepeng
    Lou, JinXing
    Bai, Xue
    Du, Junfeng
    Guo, Zhi
    Chen, Peng
    ACTA HAEMATOLOGICA, 2014, 131 (01) : 37 - 44
  • [8] Allogeneic Hematopoietic Stem Cell Transplantation for Leukocyte Adhesion Deficiency
    Horikoshi, Yasuo
    Umeda, Katsutsugu
    Imai, Kohsuke
    Yabe, Hiromasa
    Sasahara, Yoji
    Watanabe, Kenichiro
    Ozawa, Yukiyasu
    Hashii, Yoshiko
    Kurosawa, Hidemitsu
    Nonoyama, Shigeaki
    Morio, Tomohiro
    JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2018, 40 (02) : 137 - 140
  • [9] Outcomes of symptomatic venous thromboembolism after haploidentical donor hematopoietic stem cell transplantation and comparison with human leukocyte antigen-identical sibling transplantation
    Zhang, Gao-Chao
    Zhang, Yuan-Yuan
    Zeng, Qiao-Zhu
    Meng, Xing-Ye
    Zhao, Peng
    Fu, Hai-Xia
    He, Yun
    Zhu, Xiao-Lu
    Mo, Xiao-Dong
    Wang, Jing-Zhi
    Yan, Chen-hua
    Wang, Feng-Rong
    Chen, Huan
    Chen, Yao
    Han, Wei
    Wang, Yu
    Xu, Lan-Ping
    Liu, Kai-Yan
    Huang, Xiao-Jun
    Zhang, Xiao-Hui
    THROMBOSIS RESEARCH, 2020, 194 : 168 - 175
  • [10] Matched Related and Unrelated Donor Hematopoietic Stem Cell Transplantation for DOCK8 Deficiency
    Cuellar-Rodriguez, Jennifer
    Freeman, Alexandra F.
    Grossman, Jennifer
    Su, Helen
    Parta, Mark
    Murdock, Heardley
    Shah, Nirali
    Bollard, Catherine
    Kong, Heidi H.
    Moutsopoulos, Niki
    Stone, Kelly
    Gea-Banacloche, Juan
    Holland, Steven M.
    Hickstein, Dennis D.
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2015, 21 (06) : 1037 - 1045
12345