Exogenous α-synuclein induces toll-like receptor 4 dependent inflammatory responses in astrocytes

被引：0
|
作者：
Emmy H. Rannikko
Stephanie S. Weber
Philipp J. Kahle
机构：
[1] University of Tübingen,Laboratory of Functional Neurogenetics, Department of Neurodegeneration, Faculty of Medicine, Hertie Institute for Clinical Brain Research
[2] German Center for Neurodegenerative Diseases,Division of Translational Alzheimer Neurobiology, Department of Neurobiology, Care Sciences and Society
[3] Karolinska Institute,undefined
来源：
BMC Neuroscience | / 16卷
关键词：
Synuclein; Toll-like receptor TLR4; Neuroinflammation; Cytokines; Nitric oxide synthase; Cyclooxygenase; MAP kinases; NF-κB; Endocytosis; Astrocytes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Exogenous α-synuclein induces toll-like receptor 4 dependent inflammatory responses in astrocytes
    Rannikko, Emmy H.
    Weber, Stephanie S.
    Kahle, Philipp J.
    BMC NEUROSCIENCE, 2015, 16
  • [2] Toll-like receptor 4 is required for α-synuclein dependent activation of microglia and astroglia
    Fellner, Lisa
    Irschick, Regina
    Schanda, Kathrin
    Reindl, Markus
    Klimaschewski, Lars
    Poewe, Werner
    Wenning, Gregor K.
    Stefanova, Nadia
    GLIA, 2013, 61 (03) : 349 - 360
  • [3] Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo
    Woodward, Nicholas C.
    Levine, Morgan C.
    Haghani, Amin
    Shirmohammadi, Farimah
    Saffari, Arian
    Sioutas, Constantinos
    Morgan, Todd E.
    Finch, Caleb E.
    JOURNAL OF NEUROINFLAMMATION, 2017, 14
  • [4] Toll-like receptor 4 in glial inflammatory responses to air pollution in vitro and in vivo
    Nicholas C. Woodward
    Morgan C. Levine
    Amin Haghani
    Farimah Shirmohammadi
    Arian Saffari
    Constantinos Sioutas
    Todd E. Morgan
    Caleb E. Finch
    Journal of Neuroinflammation, 14
  • [5] The neurotoxic effect of astrocytes activated with toll-like receptor ligands
    Ma, Di
    Jin, Shijie
    Li, Endong
    Doi, Yukiko
    Parajuli, Bijiya
    Noda, Mariko
    Sonobe, Yoshifumi
    Mizuno, Tetsuya
    Suzumura, Akio
    JOURNAL OF NEUROIMMUNOLOGY, 2013, 254 (1-2) : 10 - 18
  • [6] Cytochrome c can be released into extracellular space and modulate functions of human astrocytes in a toll-like receptor 4-dependent manner
    Wenzel, Tyler J.
    Bajwa, Ekta
    Klegeris, Andis
    BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2019, 1863 (11):
  • [7] Toll-like receptor 4-dependent innate immune responses are mediated by intracrine corticosteroids and activation of glycogen synthase kinase-3β in astrocytes
    Lai, Wenfang
    Huang, Siying
    Liu, Junjie
    Zhou, Binbin
    Yu, Zhengshuang
    Brown, John
    Hong, Guizhu
    FASEB JOURNAL, 2024, 38 (13)
  • [8] Involvement of toll-like receptor 4 in the inflammatory reaction induced by hydroxyapatite particles
    Grandjean-Laquerriere, Alexia
    Tabary, Olivier
    Jacquot, Jacky
    Richard, Doriane
    Frayssinet, Patrick
    Guenounou, Moncef
    Laurent-Maquin, Dominique
    Laquerriere, Patrice
    Gangloff, Sophie
    BIOMATERIALS, 2007, 28 (03) : 400 - 404
  • [9] Toll-Like Receptor 4 Is a Regulator of Monocyte and Electroencephalographic Responses to Sleep Loss
    Wisor, Jonathan P.
    Clegern, William C.
    Schmidt, Michelle A.
    SLEEP, 2011, 34 (10) : 1335 - 1345
  • [10] Injury, sepsis, and the regulation of Toll-like receptor responses
    Murphy, TJ
    Paterson, HM
    Mannick, JA
    Lederer, JA
    JOURNAL OF LEUKOCYTE BIOLOGY, 2004, 75 (03) : 400 - 407
12345