Handgrip strength cutoff points to identify mobility limitation in community-dwelling older people and associated factors

被引：62

作者：

de Souza Vasconcelos K.S. ^{[1
]}

Domingues Dias J.M. ^{[1
]}

de Carvalho Bastone A. ^{[1
]}

Alvarenga Vieira R. ^{[1
]}

de Souza Andrade A.C. ^{[1
]}

Rodrigues Perracini M. ^{[1
]}

Oliveira Guerra R. ^{[1
]}

Corrêa Dias R. ^{[1
]}

机构：

[1] Physical Therapy, Universidade Federal de Minas Gerais, Rua Engenheiro Hermenegildo Campos de Almeida, 260, ap 31, Jundiaí — SP, Brasil, Jundiaí, 13208640, São Paulo

来源：

The journal of nutrition, health & aging | 2016年 / 20卷 / 3期

关键词：

gait speed; handgrip strength; mobility; older people; Sarcopenia;

D O I：

10.1007/s12603-015-0584-y

中图分类号：

学科分类号：

摘要：

Background: Sarcopenia is defined as a progressive and generalized loss of skeletal muscle mass and strength. The specific threshold of muscle weakness that leads to mobility limitations has not been identified. Objectives: To determine the best cutoff point of handgrip strength for identifying mobility limitation and to investigate the factors associated with muscle weakness and mobility limitation in community-dwelling older people. Design: Transversal study. Setting: Cities of Belo Horizonte, Barueri and Santa Cruz in Brazil. Participants: 1374 community-dwelling older people from the Frailty study in Brazilian older people (FIBRA Study). Measurements: Outcomes included muscle weakness determined according to gender-specific handgrip strength cutoff points generated by Receiver Operating Characteristic curves, mobility limitation defined as a gait speed = 0.8 m/s; and a combination of both muscle weakness and mobility limitation. Associated factors included socio-demographic variables, lifestyle, anthropometrics, health conditions, use of health services and disability. Results: The cutoff points of handgrip strength with the best balancing between sensitivity and specificity for mobility limitation were 25.8 kgf for men (sensitivity 69%, specificity 73%) and 17.4 kgf (sensitivity 60%, specificity 66%) for women. Age and disability in instrumental activities of daily living were associated with all outcomes. Women had greater odds of mobility limitation than men. Physical inactivity, body fat, diabetes, depression, sleeping disturbances, number of medications and occurrence of falls remained as significant associated factors in the final model. Conclusions: Handgrip strength can be a useful tool to identify mobility limitation in clinical practice. Interventions to prevent or minimize impacts of sarcopenia should stimulate physical activity and improvement of body composition in addition to the management of chronic diseases and disabilities. © 2016, Serdi and Springer-Verlag France.

引用

页码：306 / 315

页数：9

共 41 条

[1]

Cruz-Jentoft A.J., Baeyens J.P., Bauer J.M., Boirie Y., Cederholm T., Landi F., Martin F.C., Michel J.P., Rolland Y., Schneider S.M., Topinkova E., Vandewoude M., Zamboni M., Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People, Age Ageing, 39, pp. 412-423, (2010)

[2]

Scott D., Blizzard L., Fell J., Jones G., The epidemiology of sarcopenia in community living older adults: what role does lifestyle play, J Cachexia Sarcopenia Muscle, 2, pp. 125-134, (2011)

[3]

Rolland Y., Czerwinski S.A., Van K.G., Morley J.E., Cesari M., Onder G., Woo J., Baumgartner R., Pillard F., Boirie Y., Chumlea W.M., Vellas B., Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives, J Nutr Health Aging, 12, pp. 433-450, (2008)

[4]

Janssen I., Evolution of sarcopenia research, Appl Physiol Nutr Metab, 35, pp. 707-712, (2010)

[5]

Kim T., Yang S., Yoo H., Lim K., Hang H., Song W., Seo J., Kim S., Kim N., Baik S., Choi D., Choi K., Prevalence of sarcopenia and sarcopenic obesity in Korean adults: the Korean sarcopenic obesity study, Int j Obes, 3, pp. 885-892, (2009)

[6]

Stenholm S., Harris T., Rantanen T., Visser M., Kritchevsky S., Ferrucci L., Sarcopenic obesity:definition, cause and consequences, Curr Opin Clin Nutr Metab Care, 11, pp. 693-700, (2008)

[7]

Manini T.M., Clark B.C., Dynapenia and aging: an update, J Gerontol A Biol Sci Med Sci, 67, pp. 28-40, (2012)

[8]

McLean R., Shardel M., Alley D., Cawthon P., Fragala M., Harris T.B., Kenny A., Peters K., Ferrucci L., Guralnik J.M., Criteria for relevant weakness and low lean mass and their longitudinal association with incident mobility impairment and mortality: the foundation for the National Institutes of health (FNIH) sarcopenia project, J Gerontol A Biol Sci Med Sci, 69, pp. 576-583, (2014)

[9]

Brucki S., Nitrini R., Caramelli P., Bertolucci P., Okamoto I., Suggestions for utilization of the mini-mental state examination in Brazil, Arq Neuropsiquiatr, 61, pp. 777-781, (2003)

[10]

Fried L., Tangen C., Walston J., Et al., Frailty in Older Adults: Evidence for a Phenotype, J Gerontol, 56A, pp. M146-M156, (2001)

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