The immune system view of the coronavirus SARS-CoV-2

被引:0
作者
Ivana Celardo
Luigia Pace
Loredana Cifaldi
Carlo Gaudio
Vincenzo Barnaba
机构
[1] Sapienza Università di Roma,Dipartimento di Scienze Cliniche Internistiche, Anestesiologiche e Cardiovascolari
[2] Italian Institute for Genomic Medicine,Armenise
[3] FPO IRCCS Candiolo,Harvard Immune Regulation Unit
[4] Ospedale Pediatrico Bambino Gesù,Academic Department of Pediatrics (DPUO),
[5] ,Department of Clinical Sciences and Translational Medicine
[6] University of Rome “Tor Vergata”,undefined
来源
Biology Direct | / 15卷
关键词
COVID-19; SARS-CoV-2; Vaccine; Coronavirus; Monoclonal antibodies;
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学科分类号
摘要
Knowing the “point of view” of the immune system is essential to understand the characteristic of a pandemic, such as that generated by the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2, responsible for the Coronavirus Disease (COVID)-19. In this review, we will discuss the general host/pathogen interactions dictating protective immune response or immunopathology, addressing the role of immunity or immunopathology in influencing the clinical infection outcome, and debate the potential immunoprophylactic and immunotherapy strategies required to fight the virus infection.
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