Upregulation of IL-17A/F from human lung tissue explants with cigarette smoke exposure: implications for COPD

被引：0
作者：
Ying Chang
Laila Al-Alwan
Sama Alshakfa
Severine Audusseau
Andrea Karen Mogas
Fazila Chouiali
Parameswaran Nair
Carolyn J Baglole
Qutayba Hamid
David H Eidelman
机构：
[1] McGill University Health Centre and Department of Medicine,Meakins
[2] McGill University,Christie Laboratories and Respiratory Division
[3] Xi’an Jiaotong University,Center for Translational Medicine, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology and Frontier Institute of Science and Technology
[4] McMaster University,Firestone Institute for Respiratory Health, St. Joseph’s Healthcare and Department of Medicine
来源：
Respiratory Research | / 15卷
关键词：
COPD; IL-17; Cigarette smoke; Tissue explants;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 201 条
[1]  
Pauwels RA(2004)Burden and clinical features of chronic obstructive pulmonary disease (COPD) Lancet 364 613-620
[2]  
Rabe KF(2009)Immunologic aspects of chronic obstructive pulmonary disease N Engl J Med 360 2445-2454
[3]  
Cosio MG(2003)Hypothesis: does COPD have an autoimmune component? Thorax 58 832-834
[4]  
Saetta M(2007)Interleukin-17: a new paradigm in inflammation, autoimmunity, and therapy J Periodontol 78 1083-1093
[5]  
Agusti A(2009)Regulation of airway MUC5AC expression by IL-1beta and IL-17A; the NF-kappaB paradigm J Immunol 183 6236-6243
[6]  
Agusti A(2005)A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 Nat Immunol 6 1133-1141
[7]  
MacNee W(2009)T helper type 17-related cytokine expression is increased in the bronchial mucosa of stable chronic obstructive pulmonary disease patients Clin Exp Immunol 157 316-324
[8]  
Donaldson K(2004)Autoimmunity, T-cells and STAT-4 in the pathogenesis of chronic obstructive pulmonary disease Eur Respir J 24 3-5
[9]  
Cosio M(1991)Explant organ culture: a review Cytotechnology 7 137-149
[10]  
Kramer JM(2005)BIRB796 inhibits all p38 MAPK isoforms in vitro and in vivo J Biol Chem 280 19472-19479
12345678910