Influence of the structure of organic phosphonate compounds on chiral separation on a pirkle type chiral stationary phase

被引：0
作者：
G. -S. Yang
M. -B. Huang
Q. Dai
R. -Y. Gao
Q. -S. Wang
A. -Q. Du
G. -L. Li
机构：
[1] Shandong University,Department of Chemistry
[2] Nankai University,National Laboratory of Elemento
来源：
Chromatographia | 2001年 / 53卷
关键词：
Column liquid chromatography; Chiral stationary phase; Chiral separation; Organic phosphonate;
D O I：
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中图分类号：
学科分类号：
摘要：
The enantiomers of eightO,O-dialkyl-2-benzyloxycarbonyl-aminoarylmethyl-phosphonates are directly separated on anN-(3,5-dinitrobenzoyl)leucine (DNBleu) column. The influence of the mobile phase composition and the column temperature on the retention and the enantioselectivity are investigated. The influence of the length and steric hindrance of alkoxyl groups of the phosphonate ester and the nature of the substituentp-Cl and pH on the benzene ring which is attached to the chiral carbon atom on chiral separation are discussed also.
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页码：93 / 95
页数：2
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