共 50 条
Spotlight on Peginterferon-α-2a (40KD) in Chronic Hepatitis C
被引:0
作者:
Caroline M. Perry
Blair Jarvis
机构:
[1] Adis International Limited,
[2] 41 Centorian Drive,undefined
来源:
BioDrugs
|
2002年
/
16卷
关键词:
Chronic Hepatitis;
Sustained Virological Response;
Virological Response;
Fatigue Severity Scale;
Histological Improvement;
D O I:
暂无
中图分类号:
学科分类号:
摘要:
Peginterferon-α-2a (40KD) is a new ‘pegylated’ subcutaneous formulation of interferon-α-2a that has been developed to improve on the pharmacokinetic profile and therapeutic efficacy of interferon-α-2a. Peginterferon-α-2a (40KD) is produced by the covalent attachment of recombinant interferon-α-2a to a branched mobile 40KD polyethylene glycol moiety, which shields the interferon-α-2a molecule from enzymatic degradation, reduces systemic clearance and enables once-weekly administration.
引用
收藏
页码:213 / 217
页数:4
相关论文
共 50 条