The Effect of Helicobacter pylori on Postoperative Outcomes in Patients Undergoing Bariatric Surgery: a Systematic Review and Meta-analysis

被引：0
作者：
Valentin Mocanu
Jerry T. Dang
Noah Switzer
Daniel Skubleny
Xinzhe Shi
Chris de Gara
Daniel W. Birch
Shahzeer Karmali
机构：
[1] University of Alberta,Department of Surgery
[2] University of Alberta Hospital,Department of Surgery
[3] Royal Alexandra Hospital,Centre for the Advancement of Minimally Invasive Surgery (CAMIS)
来源：
Obesity Surgery | 2018年 / 28卷
关键词：
Helicobacter pylori; Bariatric surgery; H. Pylori; Gastric bypass; Gastric band; Sleeve gastrectomy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Helicobacter pylori (HP) occurs in 50% of people worldwide with higher rates reported in the bariatric population. HP has been associated with adverse outcomes following bariatric surgery; however, its true impact has not yet been defined. We aimed to systematically review the effect of HP on bariatric surgery outcomes. A comprehensive literature review was conducted yielding seven studies with 255,435 patients. Meta-analysis found comparable rates of bleeding, leak, hospital length of stay, and weight loss between HP-positive and HP-negative patients. HP was, however, found to be the largest independent predictor of marginal ulceration in those undergoing RYGB, with a tenfold increase versus HP-negative patients. Overall, HP is associated with increased marginal ulceration rates, but has little impact on other bariatric surgery outcomes.
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页码：567 / 573
页数：6
相关论文
共 32 条
[1]  
Rawlins L(2013)Effect of Helicobacter pylori on marginal ulcer and stomal stenosis after Roux-en-Y gastric bypass Surg Obes Relat Dis 9 760-764
[2]  
Brown LM(2000)Helicobacter pylori: epidemiology and routes of transmission Epidemiol Rev 22 283-297
[3]  
Brolin RE(2002)Bariatric surgery and long-term control of morbid obesity JAMA 288 2793-2796
[4]  
Arslan E(2009)The prevalence of Helicobacter pylori in obese subjects Eur J Intern Med 20 695-697
[5]  
Atilgan H(2014)Helicobacter pylori infection in obesity and its clinical outcome after bariatric surgery World J Gastroenterol 20 647-653
[6]  
Yavaşoğlu I(1996)Staple disruption and marginal ulceration in gastric bypass procedures for weight reduction Obes Surg 6 44-49
[7]  
Carabotti M(2007)Marginal ulceration after laparoscopic gastric bypass: an analysis of predisposing factors in 260 patients Surg Endosc 21 1090-1094
[8]  
Capella JF(2008)SAGES guidelines for clinical application of laparoscopic bariatric surgery Surg Endosc 22 2281-2300
[9]  
Capella RF(2015)The presence of Helicobacter pylori is not associated with long-term anastomotic complications in gastric bypass patients Surg Endosc 29 2885-2890
[10]  
Rasmussen JJ(2008)Prevalence of Helicobacter pylori infection and value of preoperative testing and treatment in patients undergoing laparoscopic Roux-en-Y gastric bypass Surg Obes Relat Dis 4 383-388
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